Isolation,Characterization and Biological Activity of a Dihydroflavonol From Tamarix nilotica (Tamaricaceae) Leaves.
- Sudan University of Science and Technology, Faculty of Science, Dept. of Chemistry.
- University of Kassala , Faculty of Education, Dept. of Chemistry.
- Gazira University, Faculty of Education, Dept. of Chemistry.
- Africa International University, Faculty of Pharmacy
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The authors report on the isolation,characterization and antimicrobial potency of a dihydroflavonol isolated from the leaves of Sudanese Tamarix nilotica. The isolate was purified by different chromatographic techniques and identified via a combination of spectral tools( IR, UV, 1HNMR and Mass spectroscopy). The isolated flavonoid , ethyl acetate and n-butanol fractions were evaluated(in vitro) for their antimicrobial potential against Gram negative (Escherichia coli, Salomonella typhi ) and Gram positive (Bacillus subtilis , Staphylococcus aureus) bacteria and the fungi :Candida albicans and Aspergillus niger and promising results were obtained.The isolated dihydroflavonol seems to be a suitable candidate for future optimization.
[Abdel Karim,M., Amani ,H, El Hafez. M. Alraih and Kalid,M. (2016); Isolation,Characterization and Biological Activity of a Dihydroflavonol From Tamarix nilotica (Tamaricaceae) Leaves. Int. J. of Adv. Res. 4 (6). 2048-2056] (ISSN 2320-5407). www.journalijar.com
Article DOI: 10.21474/IJAR01/797 DOI URL: http://dx.doi.org/10.21474/IJAR01/797
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