20Dec 2016

ENHANCE BIOAVABILITY OF ALBENDAZOLE DRUG BY MESOPOROUS MATERIAL.

  • School of Pharmacy (RKDF IPS), Dr. A.P.J. Abdul Kalam University Indore Bypass Road, Arandia Village, Post Jhalaria, Indore, Madhya Pradesh 452016.
  • Shri Aurbindo Institute of Pharmacy, Indore.
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Mesoporous silica nanoparticles (MSN) have gained attention for potential as controlled release systems and vechicles for the delivery of chemotherapeutics due to high surface areas, large cavity volumes and ability to be fictionalized with biomolecules for the targeting of specific tissue by using Mesoporous material with Albendazole drug enhance Bioavability. Various Mesoporous silica structure incorporation of heteroatoms such as Cu, Zn, Al and Fe etc. into Mesoporous silica framework has been investigated .Mesoporous materials are used because of their ability of their desirable characteristics such as high surface area, large pore volume, and tunable Mesoporous channels with well defined pore size distribution, controllable wall composition as well as modification surface properties. According to the nomenclature by International Union of pure and applied chemistry (IUPAC). Albendazole is an antihelmintic drug whose solubility is low by Using Mesoporous material than Bioavability of Albendazole are Enhanced.


[Paras Bodana, Girver Kelkar, Shelendra Kumar Manglavat, Arun Kumar Gupta and S. C. Chaturvedi. (2016); ENHANCE BIOAVABILITY OF ALBENDAZOLE DRUG BY MESOPOROUS MATERIAL. Int. J. of Adv. Res. 4 (Dec). 2518-2530] (ISSN 2320-5407). www.journalijar.com


Paras Bodana


DOI:


Article DOI: 10.21474/IJAR01/2677      
DOI URL: http://dx.doi.org/10.21474/IJAR01/2677