20Mar 2017

COMPARATIVE EVALUATION OF ANTIMICROBIAL POTENTIAL OF GINGER, GARLIC AND CINNAMON EXTRACTS AGAINST STREPTOCOCCUS MUTANS AND LACTOBACILLUS ACIDOPHILUS.

  • MDS, Department of Pedodontics, K. D. Dental College and Hospital, Mathura, Uttar Pradesh, India.
  • MDS, Reader, Department of Pedodontics, K. D. Dental College and Hospital, Mathura, Uttar Pradesh, India.
  • MDS, Professor and Head, Department of Pedodontics, K. D. Dental College and Hospital, Mathura, Uttar Pradesh, India.
  • MDS, Senior lecturer, Department of Pedodontics, Purvanchal Institute of Dental Sciences, Gorakhpur, Uttar Pradesh, India.
  • MDS, Professor, Department of Pedodontics, K. D. Dental College and Hospital, Mathura, Uttar Pradesh, India.
  • MDS, Former Reader, Department of Pedodontics, K. D. Dental College and Hospital, Mathura, Uttar Pradesh, India.
Crossref Cited-by Linking logo
  • Abstract
  • Keywords
  • References
  • Cite This Article as
  • Corresponding Author

Aim and Objective: To evaluate the antibacterial potential of herbs and spices extracts in efficiently reducing cariogenic pathogens in oral cavity, thereby incorporating them into various dentifrices and topical preparations which are safe, economical, free from side effects and could act as the new source of antimicrobial agents. Methods: Ethanolic extracts (10% each) of ginger, garlic and cinnamon were prepared and subjected to microbiological assay along with 0.2% chlorhexidine gluconate (CHX), to determine its zone of inhibition at volumes of 10 µl, 20 µl, and 30µl each using Agar disk diffusion test against Streptococcus mutans (S.mutans) and Lactobacillus acidophilus (L.acidophilus). One-way ANOVA test and Post hoc test were used to compare the antibacterial potential of herbs and spices extracts in efficiently reducing cariogenic pathogens in oral cavity by incorporating them into various dentifrices using SPSS software version 14. The significance level for all the statistical tests utilized in this study was set at p < 0.05 %. Results: There was a significant correlation between the control and experimental groups. The highest antimicrobial efficacy was observed in positive control group and by 10% ethanolic Cinnamon extract in comparison to 10% ethanolic extracts of Ginger and Garlic. Conclusion: The plant extracts such as Cinnamon extracts in 10% concentration could be used as an alternative antibacterial compound for effective reduction of cariogenic pathogens in oral cavity.

  1. Lakade LS, Shah P, Shirol D. Comparison of antimicrobial efficacy of chlorhexidine and combination mouth rinse in reducing the Mutans streptococcus count in plaque. J Ind Soc Pedod Prev Dent 2014; 32(2):91-96.
  2. Akhani SP, Vishwakarma SL, Goyal RK. Anti-diabetic activity of Zingiber officinale in streptozotocin-induced type I diabetic rats. J Pharm Pharmacol 2004; 56:10-5.
  3. Gull I, Saeed M, Shaukat H, Aslam SM, Samra ZQ, Athar AM. Inhibitory effect of Allium sativum and Zingiber officinale extracts on clinically important drug resistant pathogenic bacteria. Ann Clin Microbiol Antimicrob 2012; 11(8): 1-6.
  4. Panpatil VV, Tattari S, Kota N, Nimgulkar C, Polasa K. In vitro evaluation on antioxidant and antimicrobial activity of spice extracts of ginger, turmeric and garlic. J Pharm Phytochem 2013; 2(3): 143-148.
  5. Gautam A, Kashyap SJ, Sharma PK, Garg VK, Visht S, Kumar N. Identification, evaluation and standardization of herbal drugs: A review. Der Pharmacia Lettre 2010; 2(6): 302-315.
  6. Owhe-Ureghe UB, Ehwarieme DA, Eboh DO. Antibacterial activity of garlic and lime on isolates of extracted carious teeth. African J Biotech 2010; 9(21): 3163-3166.
  7. Sheen S, Addy M. An in vitro evaluation of the availability of cetylpyridinium chloride and chlorhexidine in some commercially available mouthrinse products. Br Dent J 2003; 194(4): 207-210.
  8. Jain I, Jain P, Bisht D, Sharma A, Srivastava B, Gupta N. Use of traditional Indian plants in the inhibition of caries causing bacteria - Streptococcus mutans. Braz Dent J 2015; 26 (2): 110-115.
  9. Ross ZM, O’Gara EA, Hill DJ, Sleightholme HV, Maslin DJ. Antimicrobial properties of garlic oil against human enteric bacteria: evaluation of methodologies and comparisons with garlic oil sulfides and garlic powder. App Env Microbio 2001; 67(1): 475-480.
  10. Rashad JM. Effect of water cinnamon extract on mutans Streptococci, in comparison to chlorhexidine gluconate and Zac (in-vitro and in-vivo study). Marietta Daily J 2008; 5 (3): 250-260.
  11. Burt S. Essential oils: their antibacterial properties and potential applications in foods—a review. Int J Food Microbiol 2004; 94: 223-253.
  12. Marren K. Dimethyl sulfoxide: an effective penetration enhancer for topical administration of NSAIDs. Physician Sports Med 2011; 39:75-82.
  13. Nanasombat S, Lohasupthawee P. Antibacterial activity of crude ethanolic extracts and essential oils of spices against salmonellae and other enterobacteria. KMITL Sci Tech J 2005; 5:527-538.
  14. Ajay Rao HT, Bhat SS, Hegde S, Jhamb V. Efficacy of garlic extract and chlorhexidine mouthwash in reduction of oral salivary microorganisms: An in vitro study. Anc Sci Life 2014; 34(2): 85-88.
  15. Asimi OA, Sahu NP, Pal AK. Antioxidant activity and antimicrobial property of some Indian spices. Int J Sci Res Pub 2013; 3(3):1- 8.

[Priti Yadav, Sonal Gupta, Chanchal Singh, Siddharth Anand, Updesh Masih and Deepa Hegde Y. (2017); COMPARATIVE EVALUATION OF ANTIMICROBIAL POTENTIAL OF GINGER, GARLIC AND CINNAMON EXTRACTS AGAINST STREPTOCOCCUS MUTANS AND LACTOBACILLUS ACIDOPHILUS. Int. J. of Adv. Res. 5 (Mar). 332-336] (ISSN 2320-5407). www.journalijar.com

Siddharth Anand
MDS, Senior lecturer, Department of Pedodontics, Purvanchal Institute of Dental Sciences, Gorakhpur, Uttar Pradesh, India

DOI:

Article DOI: 10.21474/IJAR01/3519      
DOI URL: http://dx.doi.org/10.21474/IJAR01/3519

Download Full Paper

Download PDF No. of Downloads: 106 | No. of Views: 307