20Mar 2017

A CLINICAL STUDY TO COMPARE THE EFFICACY OF AUTOLOGUS PLATELET RICH PLASMA (PRP) VERSUS NORMAL SALINE DRESSING IN CHRONIC NON-HEALING ULCERS

  • Assistant professor, Dept. Of Plastic Surgery, Government Medical College and ESI Hospital, Coimbatore.
  • Professor Of Plastic Surgery &Dean Government Medical College and ESI Hospital, Coimbator.
  • Associate Professor.Dept. Of Plastic Surgery-CMCH,Coimbatore
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  1. Crovetti G, Martinelli G, Issi M, Barone M, Guizzardi M, Campanati B et al. Platelet gel for healing cutaneous chronic wounds. Transfus Apheres Sci 2004 Apr;30(2):145-151. [PubMed] [CrossRef)
  2. Cancela AM, Lana JF, Annichino-Bizzachi JM, Belangero WD, Luzo AC. Use of Platelet-Rich Plasma (PRP) in Treating Chronic Wounds. In: Lana JF, et al. (eds.), Platelet-Rich Plasma. Lecture Notes in Bioengineering. Springer-Verlag Berlin, Heidelberg. 2014; p281-288. [CrossRef]
  3. Marx RE Platelet-rich plasma (PRP): what is PRP and what is not PRP? Implant Dent. 2001 Dec; 10(4):225-228. [PubMed] [CrossRef]
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  5. Fu X, Li X, Cheng B, Chen W. Sheng Z. Engineered growth factors and cutaneous wound healing: Success and possible questions in the past 10 years. Wound Repair Regen. 2005 Mar- pr;13(2):122-130. [PubMed] [CrossRef]
  6. Lana JF, Weglein A, Vicente E, Perez AG, Rodrigues AA, Luzo AC, at al. Platelet Rich Plasma and Its Growth Factors: The State of the Art. In: Lana JF, et al. (eds.), Platelet-Rich Plasma. Lecture Notes in Bioengineering. Springer-Verlag Berlin, Heidelberg. 2014; p1-59. [CrossRef]
  7. Mehta S,Watson JT. Platelet rich concentrate: basic science and current clinical applications. J Orthop Trauma. 2008;22(6):432-8.
  8. Marx RE. Platelet-rich plasma (PRP): what is PRP and what is not PRP? Implant Dent. 2001;10(4):225-8.
  9. Driver VR, Hanft J, Fylling CP, Beriou JM,Autologel Diabetic Foot Ulcer Study Group. A prospective, randomized, controlled trial of autologous platelet-rich plasma gel for the treatment of diabetic foot ulcers. Ostomy Wound Manage. 2006;52(6):68-70, 72, 74 passim.
  10. Virchenko O, Aspenberg P. How can one platelet injection after tendon injury lead to a stronger tendon after 4 weeks? Interplay between early regeneration and mechanical stimulation. Acta Orthop. 2006 Oct; 77(5):806-812. [PubMed] [CrossRef]
  11. Weibrich G, Kleis WKG, Hafner G, Hitzler WE. Growth factor levels in platelet-rich plasma and correlations with donor age, sex, and platelet count. J Craniomaxillofacial Surg.2002 Apr; 30(2):97-102. [PubMed] [CrossRef]
  12. Driver VR, Hanft J, Fylling CP, Beriou JM. A prospective, randomized, controlled trial of autologous platelet-rich plasma gel for the treatment of diabetic foot ulcers. Ostomy Wound Manage. 2006 Jun; 52(6):68-
  13. .Marx RE. Platelet-rich plasma (PRP): what is PRP and what is not PRP? ImplantDent
  14. Frykberg RG, Driver VR, Carman D, Lucero B, Borris-Hale C, Fylling CP, Rappl LM, Clausen PA.                 Chronic wounds treated with a physiologically relevant concentration of platelet-rich plasma gel: a      prospective case series. Ostomy Wound Manage 2010;56:36?
  15. Steenvoorde P, van Doorn LP, Naves C, Oskam J. Use of autologous plateletrich fibrin on hard-to-heal   J Wound Care 2008;17:60?3
  16. Kakudo N, Kushida S, Ogura N, Hara T, Suzuki K. The use of autologous platelet rich plasma in the  treatment of intractable skin ulcer. Open J Reg Med 2012;1:29?32
  17. Dohan DM, Choukroun J, Diss A, Dohan SL, Dohan AJ, Mouhyi J, Gogly B. Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part III leucocyte activation: a new feature for platelet concentrates? Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;101:e51?

[S. Sivakumar. Mch, B. Asokan. Mch, V. P. Ramanan. Mch, M. Sundrarajan .Mch. (2017); A CLINICAL STUDY TO COMPARE THE EFFICACY OF AUTOLOGUS PLATELET RICH PLASMA (PRP) VERSUS NORMAL SALINE DRESSING IN CHRONIC NON-HEALING ULCERS Int. J. of Adv. Res. 5 (Mar). 363-371] (ISSN 2320-5407). www.journalijar.com

DR.S.SIVAKUMAR
GOVERMENT MEDICAL COLEGE AND ESI HOSPITAL

DOI:

Article DOI: 10.21474/IJAR01/3521      
DOI URL: http://dx.doi.org/10.21474/IJAR01/3521

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