17Jul 2017

STUDY OF DRUG PRESCRIBING AND USE PATTERN IN PAEDIATRIC BRONCHIAL ASTHMA PATIENTS.

  • Department of Pharmacy Practice, Rajah Muthiah Medical College and Hospital (RMMCH), Chidambaram-608001, India.
  • Department of Pharmacy, Annamalai University, Chidambaram-608001, India.
Crossref Cited-by Linking logo
  • Abstract
  • Keywords
  • References
  • Cite This Article as
  • Corresponding Author

Background: Asthma is a condition in which a persons airways become inflamed,narrow and swell and produce extra mucus, which makes it difficult to breathe. Aim and Objective: This study aims on describing the drug prescribing pattern,medication adherence,quality of life,handling of inhalers,lung function test and cost of illness in 110 paediatric bronchial asthma patients in a tertiary care hospital for duration of six months. Results: Overall 110 patients were enrolled in the study and its found that male patients (60.90%) are more prone to asthmatic attacks than female patients (39.10%). β-agonists (Salbutamol,) was the most commonly used bronchodialator followed by corticosteroids(82.72%), antibiotics(56.36%),anti-histamines(30%)anti inflammatory(29.9%),anti-tussives(23.63%) and methylxanthines(11.81%). Drugs used in RMMCH were compared to various EDL (Essential drug list) which complied with national EDL.The FVC and FEV were assessed among the patients during their admission and discharge time.The statistical analysis of the data of the two groups (baseline and discharge) for FVC(P=<0.001) and FEV(p=<0.008) shows its significance.20.9%.61.81%.80.9% of the patients has shown correct usage of inhalers during baseline,after first and second counseling.A significant improvement in quality of life was assessed during pre and post counseling using Mann-Whitney rank sum test.The score of low(55.45%) medium(32.72%) and high(11.81%)medication adherence patients was found on pre-counseling and on post-counseling low(17.27%),medium(55.45%) and high(28.18%) medication adherence was observed.Hospitalization charges are accounting for 39.3% and medical charges are accounting for 24.21%on an average of 6 days of admission in the hospital. Conclusion: Patient counseling aided and had a positive impact on patients understanding of their illness and the role of medications in its treatment,improved medication adherence and improved quality of life for the patients.


  1. Joseph Dipiro T, Robert Talbert L, Gary Yee C, et al. pharmacotherapy A Pathophysiologic Approach. 7th McGraw hill; 463.
  2. Johnston SL, Holgate ST, editors. Asthma: critical debates. London: Blackwell science; 2003.
  3. Rabe KF, Adachi M, Lai CK. Worldwide severity and control of asthma in children and adults: the global asthma insights and reality surveys. J Allergy 2004; 114(1): 40-7.
  4. Herfindal Eric T, Helms RA, Quinn DJ. Text book of Therapeutics. 2nd ed. Lippincot William and Wilkins; 2002. 658-81.
  5. World health organization.? bronchial asthma, fact sheet N?206.? [Internet] Available from: http://www.who.int/mediacentre/factsheets.
  6. Donahue JG, Weiss ST, Livingstone JM, et al. Inhaled steroids and the risk of hospitalization for asthma. JAMA. 1997; 277(11): 887-91.
  7. Martin Schulz, Frank Verheyen, et al. pharmaceutical care services for asthma patients a controlled intervention study. Journal of clinical pharmacology. The American college of clinical pharmacology 2001; 41(1): 668-76.
  8. Book of adherence to long term therapies- evidence for action- WHO; 2003. 20.
  9. Morisky DE, Ang A, Krousel-Wood M, Ward HJ. Predictive validity of a medication adherence measure m an outpatient setting. J Clins Hypertens. 2008; 10(5): 348-54.
  10. Patel Pinal D, patel RK, patel N J, et al. Analysis of prescription pattern and drug utilization in asthma therapy. IRJP. 2012; 108(1): 257.
  11. Stock S, Redaelli M, Luengen M, Wendland G, Civello D. Lauterbach Asthma: prevalence and cost of illness. Eur Respir J. 2005; 25: 47-53
  • Wendy Ungar J, Peter Coyte C, et al. Prospective Study of the Patient- Level Cost of Asthma Care in Children. Pediatric Pulmonology 2001; 32(2): 101-8.
  • Chamanpreet S, Gandhi, et al. Assessment of Quality of Life in Children with Asthma and Epilepsy Pediatrics. an open access journal ISSN: 2161-
  • Mike Thomas, Tarita Murray-Thomas, Tao Fan. Prescribing patterns of asthma controller therapy for children in UK primary care: a cross-sectional BMC Pulmonary Medicine 2010; 10(1):? ? http://www.biomedcentral. com/1471-2466/10/29
  1. Gallefoss F, Bakke PS, Rsgaard P. Quality of life assessment after patient education in a randomized controlled study on asthma and chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 1999; 159(3): 812.
  2. Jones PW, Quirk FH, BaveystockCM, Littlejohns P. A self-complete measure of health status for chronic airflow limitation. Am. Rev. Respir. Dis. 1992; 145(6): 1321-7.
  3. Arellano FM, Arana A, Wentworth CE, Vidaurre CF, Chipps BE. Prescription patterns for asthma medications in children and adolescents with health care insurance in the United States. Pediatr Allergy Immunol. 2011; 22(5): 469-76.

[Minju Saji, Lida Elizabeth Raju, Sagy P Thomas, P. K. Manna., S. Ramesh and Saravanan. S. (2017); STUDY OF DRUG PRESCRIBING AND USE PATTERN IN PAEDIATRIC BRONCHIAL ASTHMA PATIENTS. Int. J. of Adv. Res. 5 (Jul). 691-698] (ISSN 2320-5407). www.journalijar.com


MINJU SAJI,LIDA ELIZABETH RAJU,SAGY P.THOMAS
ANNAMALAI UNIVERSITY

DOI:


Article DOI: 10.21474/IJAR01/4769      
DOI URL: http://dx.doi.org/10.21474/IJAR01/4769