GC-MS ANALYSIS AND ANTIMICROBIAL ACTIVITY OF SAUDI FOENICULUM VULGARE MILL.(APIACEAE) FIXED OIL.
- Sudan University of Science and Technology, Faculty of Science, Dept. of Chemistry.
- Najran University,Faculty of Science and Arts, Dept. of Chemistry.
- International University of Africa, Faculty of Pharmacy.
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Foeniculum vulgare seed oil was studied by GC-MS. The oil was also assessed for antimicrobial activity. Thirty two components were detected by GC-MS analysis. Main constituents are: 9-octadecenoic acid methyl ester(48.54%), 9,12-octadecadienoic acid methyl ester(28.50%), γ-terpinene(4.98%), and β-pinene(3.51%).The antibacterial activity of the oil was evaluated via the diffusion assay against five standard human pathogens(Gram positive: Staphylococcus aureus and Bacillus subtilis; Gram negative : Escherichia coli and Pseudomonasa aeruginosa and the fungus Candida albicans ) . Foeniculum vulgae oil showed excellent activity against Staphylococcus aureus in the concentration range : 100-25mg/ml. It also exhibited significant activity against the yeast Candida albicans at 100mg/ml..It seems that the oil is a lead for further optimization.
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[Abdel Karim. M., Ayda A. and Khalid M.S.. (2017); GC-MS ANALYSIS AND ANTIMICROBIAL ACTIVITY OF SAUDI FOENICULUM VULGARE MILL.(APIACEAE) FIXED OIL. Int. J. of Adv. Res. 5 (Jul). 1523-1528] (ISSN 2320-5407). www.journalijar.com
1. Sudan University of Science and Technology, Faculty of Science, Dept. of Chemistry