20Jul 2017

IMPACT OF NUTRACEUTICAL STIRRED YOGHURT ON OSTEOPOROSES USING THE OVARIECTOMIZED FEMALE WISTER RAT.

  • Animal Production Res. Institute, Agric. Res. Center, Ministry of Agric. Egypt.
  • Food science Dept., Fac. of Agric., Ain Shams University.
  • Institute of African Research and Studies, Cairo University.
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The present study was conducted to evaluate the effect of using natural stirred yoghurt (A), stirred yoghurt fortified with oats (5%) and mango (15 %) (B) and stirred yoghurt fortified with calcium silicate and mango (C) on ovariectomy (OVX) rats. Female Wister rats aged 8?10 weeks were divided into three groups: healthy (control), OVX, and OVX with therapy (1 ml Fosamax drug). Each group subdivided into four groups; three groups treated with oral administration of 7 ml stirred yoghurt (A) , (B) ,(C) and compared with untreated groups for five weeks experimental period. Serum calcium (Ca), phosphorous (P), alkaline phosphatase (ALP) and bone mineral density (BMD) were measured. The results revealed that no significant difference in serum Ca, P and ALP of healthy group with administration of stirred yoghurt treatments. Also, data showed that no significant change in Ca and P concentration of OVX rats, while very highly significant decreasing in serum ALP and BMD compared with healthy group. It was found that Fosamax drug decreased significant ALP activity and increased BMD in OVX group. Similar results were observed with administration of stirred yoghurt (A), (B) and (C). The improvements of BMD in OVX groups treated with A, B and C were significantly high compared with OVX treated with Fosamax alone. However, it was found that BMD in OVX treated with B and C yoghurt was the highest compared with A. It concluded that fortified stirred yoghurt (A, B, C) may be contribute in preventing osteoporosis disease. While, fortified stirred yoghurt (B) and (C) enhanced the results with the best result in treatment (B).

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[Mounira M. Ahmed, Magda Abd El Aziz, Sobhy H. M., Azer W. Z and El Nawawy M. A. (2017); IMPACT OF NUTRACEUTICAL STIRRED YOGHURT ON OSTEOPOROSES USING THE OVARIECTOMIZED FEMALE WISTER RAT. Int. J. of Adv. Res. 5 (Jul). 1261-1266] (ISSN 2320-5407). www.journalijar.com

Mounira M. Ahmed
Animal Production Res. Institute, Agric. Res. Center, Ministry of Agric. Egypt

DOI:

Article DOI: 10.21474/IJAR01/4836      
DOI URL: http://dx.doi.org/10.21474/IJAR01/4836

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