18Sep 2017

A STUDY OF CEREBRAL VENOUS THROMBOSIS IN PREGNANCY AND PUERPERIUM.

  • Post graduate student in the Department of Obstetrics and Gynecology, Sri Devraj URs Medical college, Sri Devraj URs Acadamy of higher Education and Research (SDUAHER), Kolar, Karnataka, India.
  • Professor in the Department of Obstetrics and Gynecology, Sri Devraj URs Medical college, Sri Devraj URs Acadamy of higher Education and Research (SDUAHER), Kolar, Karnataka, India.
  • Professor in the Department of Radiodignosis, Sri Devraj URs Medical college, Sri Devraj URs Acadamy of higher Education and Research (SDUAHER), Kolar, Karnataka, India.
  • Professor in the Department of Obstetrics and Gynecology, Sri Devraj URs Medical college, Sri Devraj URs Acadamy of higher Education and Research (SDUAHER), Kolar, Karnataka, India.
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Background: We reported a case series of cerebral vein thrombosis (CVT) in women who are pregnant or in puerperium period. We evaluated the clinical features of pregnancy-related CVT populations, including disease onset and development, imaging features, diagnosis, treatments, and patient prognosis. Methods: This study was a retrospective case series of 6 patients with diagnosis of CVT, who were admitted and was treated in R.L. Jalappa Hospital and research center, Tamaka, Kolar, Karnataka. The duration of the study was one year from October 2015 to October 2016. Results: All the patients had no history of thrombosis before. They were treated conservatively with low molecular weight heparin and mannitol. They did not have other possible risk factors for CVT. Headache was the most common symptoms and seen in 6/6 patients (100%) followed by vomiting and seizures. Conclusion: We found that high rate of CVT in women with pregnancy and puerperium and indicates that it needs be considered as a specific risk factor and should also be considered by healthcare system in order to prevent the complications.

  1. Aniket S. Kakade, Yashwant S. kulkarni. Cerebral venous thrombosis in pregnancy.BHJ. 2011; 53: 414-416.
  2. Biousse V, Bousser MG. Cerebral venous thrombosis. Neurologist.1999;5:236-249.
  3. .C, James.A ,Jick H. Clinical risk factors for venous thromboembolus in users of the combined oral contraceptive pill. Br J ClinPharmacol 2002; 53(6): 637-40.
  4. Crassard I, Ameri A, Rougemont D, Bousser MG. Thrombosesveineusesc?r?brales. EncyclM?dChirNeurologie. 2003; 17- 046-R-10 : 12.
  5. Crassard Isabelle, Soria Claudine, Tzourio Christophe, Woimant France, et al. A Negative D-Dimer Assay Does Not Rule Out Cerebral Venous Thrombosis. A Series of Seventy-Three Patients. Stroke.2005;36:1716
  6. Ciccone Alfonso, Canha O Patricia, Falca O Filipa, Ferro Jose ́ M, Sterzi Roberto. Thrombolysis for Cerebral Vein and Dural Sinus Thrombosis. Stroke.2004;35:2428.
  7. Cerebral Venous Thrombosis in Adults: A Study of 40 Cases from Saud Arabia. Stroke. 1995;26(7):1193-1195.
  8. Diana A de souse, Patricia C, Jose M. Safety of pregnancy after Cerebral Venous Thrombosis.AHA.2016;47:713-718.
  9. Dentali F, Gianni M, Crowther MA, Ageno W. Natural history of cerebral vein thrombosis: a systematic review. Blood 2006; 108(4): 1129-34.
  10. Einh?upl KM, Villringer A, Habert RL. Clinical spectrum of sinus venous thrombosis in Cerebral sinus thrombosis: experimental and clinical aspects. 1990.
  11. Ferro Jos? M, Canh?oPatr?cia, Stam Jan, Bousser Marie- Germaine, Barinagarrementeria Fernando. Prognosis of Cerebral Vein and Dural Sinus Thrombosis Results of the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT). Stroke. 2004;35(3):664-670.
  12. Jick H, Jick SS, Gurewich V, Myers MW, Vasilakis C. Risk of idiopathic cardiovascular death and nonfatal venous thromboembolism in women using oral contraceptives with differing progestagen components. Lancet 1995; 346(8990): 1589-93.
  13. Marie-Germaine Bousser, Jos? M Ferro. cerebral venous thrombosis: an update. Lancet Neurol. 2007; 6(2): 162-70.
  14. Niksirat A, Ghoreishy A, ShoghliAR,Kolifarhood G, Yousefian F. Incidence ofcerebral venous thrombosis in Iranian women: a longitudinal two-year study in Zanjan province of Iran. J Pioneer Med Sci2014; 4(1): 28-31.
  15. Prakesh C, Bansal BC. Cerebral Venous Thrombosis. JIACM: 2012;5(1). 55-61.
  16. Saadatnia M, Zare M, Fatehi F, AhmadiA.The effect of fasting on cerebral venous and Dural sinus thrombosis. Neurol Res 2009;31(8): 794-8.
  17. Saidee M, Froghipoor M, Sasannejad P, MellatArdakani A, Azarpazhooh MR. The relation between short course oral contraceptive consumption and cerebral vein thrombosis in Ramadan. Iran J Neurol 2008; 7(23): 260-5.
  18. Sasannejad P, Mellat AA, Velayati A, Shoeibi A, Saeidi M, Foroughipour M, et al. Cerebral vein thrombosis in women using short course oral contraceptive consumption. Iran J Reprod Med 2012;10(6): 537-42.
  19. Scoditti U, Buccino GP, Pini M, Pattacini C, Mancia D. Risk of acute cerebrovascular events related to low oestrogen oral contraceptives treatment. Ital J NeurolSci 1998; 19(1): 15-9.
  20. Sheeba M, Harsha S, Sumedha G, Manjula S, Pratime M. Cerebral Venous Thrombosis in Pregnancy ? A Poignant Allegory of an unsual case. JCDR. 2016; 10 (12): 8-9.
  21. Siritho S, Thrift AG, McNeil JJ, You RX,Davis SM, Donnan GA. Risk of ischemic stroke among users of the oral contraceptive pill: The Melbourne Risk Factor Study (MERFS) group. Stroke 2003; 34(7): 1575-80.
  22. Prakesh C, Bansal BC. Cerebral Venous Thrombosis. JIACM: 2012;5(1). 55-61.
  23. Tatlisumak T, Jood K, Putaala J. Cerebral Venous Thrombosis Epidemiology in Change. AHA. 2016; 47: 2169-2170.
  24. Wasay M, Bakshi R, Kojan S, Bobustuc G, Dubey N, Unwin DH. Nonrandomized Comparison of Local Urokinase Thrombolysis Versus Systemic Heparin Anticoagulation for Superior Sagittal Sinus Thrombosis. Stroke. 2001;32(10):2310-2317.
  25. Zhang Zaiqiang et al. Cerebral venous sinus thrombosis: a clinical study of 23 cases. Chinese Medical journal. 2000. 113 (11); 1043-1045.

[Dr. Ph. Priyadarshini, Dr. Munikrishna, Dr. Anil Kumar Sakalecha and Dr. Gomathy. E. (2017); A STUDY OF CEREBRAL VENOUS THROMBOSIS IN PREGNANCY AND PUERPERIUM. Int. J. of Adv. Res. 5 (Sep). 581-586] (ISSN 2320-5407). www.journalijar.com

Dr. Phurailatpam. Priyadarshini
Post Graduate, Department of Obstetrics and Gynaecology

DOI:

Article DOI: 10.21474/IJAR01/5363      
DOI URL: http://dx.doi.org/10.21474/IJAR01/5363

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