13May 2018

ANTIENCEPHALITIC ACTIVITIES OF BIOACTIVE SUBSTANCES PARTIALLY PURIFIED FROM LIRIOPE PLATYPHYLLA TUBER.

  • National Institute of Biological Resources (NIBR), Environmental Research Complex, Incheon 22689, South Korea.
  • Gyeongsangnam-do Agricultural Research & Extension Services, Jinju, 52733, South Korea.
  • Department of Agronomy & Medicinal Plant Resources, Gyeongnam National University of Science and Technology, Jinju, 52725, South Korea.
  • Swine Science and Technology Center, Gyeongnam National University of Science & Technology, Jinju 52725, South Korea.
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The Goal of this study was to identify whether the extract of Liriope platyphylla tuber can induce antiencephalitis. The yield of the hot water extraction was 1.5 times higher than the extract by simple homogenization. When the methanol fractionation after the hot water extract was done, the precipitated pellet in 70% methanol showed the highest antiencephalitis activity. In organic solvent partition after 70% methanol extract, the water phases in hexane, chloroform and ethyl acetate were exhibited higher activities, whereas its activity in butanol partition was divided into water and butanol layers. The eluents from the Sep-Pak R18 cartridge by fraction derived from the butanol and water phases in butanol partition showed the highest activity in the fraction of the hexane: ethyl acetate (5: 5) and ethyl acetate, respectively. It is assumed that the antiencephalitic activity is maintained not only in the hydrophilic materials but also in the hydrophobic ones. Therefore, we suggest that specific metabolites retained in L. platyphylla tuber are a high possibility to be applied as antiencephalitic agents.

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[Woo Young Bang, Chi Won Noh, Seung-Ho Jeon, Yeon Jo Ha, Jeong Mi Kang, Chae Won Lee, Il-Suk Kim, Tae Wan Kim and Sam Woong Kim. (2018); ANTIENCEPHALITIC ACTIVITIES OF BIOACTIVE SUBSTANCES PARTIALLY PURIFIED FROM LIRIOPE PLATYPHYLLA TUBER. Int. J. of Adv. Res. 6 (May). 109-115] (ISSN 2320-5407). www.journalijar.com

Sam Woong KIm
Gyeongnam National University of Science and Technology

DOI:

Article DOI: 10.21474/IJAR01/7013      
DOI URL: http://dx.doi.org/10.21474/IJAR01/7013

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