01Jan 2017

NESTROFT AS A SCREENING TEST FOR BETA THALASSEMIA

Abstract


NESTROFT (Naked Eye Single Tube Red Cell Osmotic Fragility Test) is simple, inexpensive and very sensitive test for screening of beta thalassemia, a form of congenital hemolytic anemia. , It is used to assess osmotic fragility of red cells at a single concentration of buffered saline (0.36% in single tube) visually without a spectrophotometer. Positive NESTROFT indicates decreased red cell osmotic fragility and increased resistance to osmotic lysis. Here we studied 100 random cases and positive cases were later confirmed by HbA2 electrophoresis.


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[Dr.Himaxi Rathod, Dr.Nandita Mehta, Dr.Priyanka Gohel (2014); NESTROFT AS A SCREENING TEST FOR BETA THALASSEMIA Int. J. of Adv. Res. 2 (8). 0] (ISSN 2320-5407). www.journalijar.com


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