Studying the Relationship Between Oxidative Stress Malondialdehyde and Heamatological Parameters in patients With Asthma in AL-Muthanna Province- Iraq

Abstract: Bronchial asthma is one of very common diseases in iraq. Exposing the body to high oxidizing agent daily during the work will cause a failure of the defense system (immunity system) to protect of the body, which increase the number of oxidizing agent in the body which known as vintage (oxidative stress) which consider as mean factor risk for many diseases one of them is Bronchial asthma. This work aims to investigate oxidative status in asthmatic patients as a measure of oxidative stress that may affect hematological parameters. Oxidant malondialdehyde (MDA) parameter was estimated in blood samples. The results of the malodialdehyde parameter of patients was compared to that of the normal control group. The results showed that samples of asthmatics group had high rates of oxidative stress. The results also showed a significant decline in most the blood indices as well as blood cell count as compared to the control group. Whereas, erythrocyte sedimentation rate was higher in male and female asthmatic patients as compared to the control group. In conclusion, the study reveals a critical increase in oxidant status accompanied by a decline in hematological parameters that may lead to permanent inflammation if not diagnosed early and treated.

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[Abeer M.A. AL-Karawyi, Marwa M.A. AL-Karawyi (2014); Studying the Relationship Between Oxidative Stress Malondialdehyde and Heamatological Parameters in patients With Asthma in AL-Muthanna Province- Iraq Int. J. of Adv. Res. 2 (12). 0] (ISSN 2320-5407). www.journalijar.com

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