Evaluation of the Osteogenic Potential of the Platelet-rich plasma and Autologous Cancellous bone grafts on Caudolateral ulna ostectomies of Nigerian local dogs

The osteogenic effects of the Platelet rich plasma (PRP) and autologous cancellous bone grafts (ACBG) on caudolateral ulna ostectomies were evaluated in 12 Nigerian local dogs. Partial ostectomy of the caudal cortical surface of the left ulna was performed under general anaesthesia. They were grouped into four groups namely; platelet rich plasma group (PRPG), cancellous bone graft group (CBG), platelet rich plasma/cancellous bone graft group (PRP/CBG) and control group (CG).The defects were treated as follows: PRPG, with autologously PRP; CBG with autologous bone graft; PRP/CBG with both autologous PRP and bone graft and the CG with normal saline before closure. Post treatment radiographs were taken at weeks 1, 6 and 8. Callus proliferation, mineralization and the radiographic optical densities (ROD) of the osteoid were compared. The PRP/CBG defects showed superior osteogenic indices. The PRP group however, performed better than the CBG group.