01Jan 2017

AMELIORATING POTENTIAL OF LYCOPENE AGAINST CADMIUM TOXICITY IN KIDNEY OF ALBINO MICE

Abstract


Cadmium is a known industrial pollutant which accumulates in the kidney and its exposure leads to the production of reactive oxygen species (ROS). The present study was carried out to evaluate the ameliorating effects of lycopene against CdCl2 induced toxicity in kidney of albino mice. The biochemical alterations in kidney tissue were observed. The results showed that cadmium administration elevated serum urea and creatinine levels and showed reduction in the content of glycogen, cholesterol and total proteins in kidney. Lycopene treatment prevented degenerative changes induced by CdCl2 and also aided in reduction of oxidative stress and restored the biochemical changes occurring in kidney tissue.


Cite This Article as:


[Suman Sharma and P.Vijaya (2015); AMELIORATING POTENTIAL OF LYCOPENE AGAINST CADMIUM TOXICITY IN KIDNEY OF ALBINO MICE Int. J. of Adv. Res. 3 (2). 0] (ISSN 2320-5407). www.journalijar.com


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