Histochemical Effects of Carbohydrates on Liver of Mancozeb Induced Albino Mice
Abstract: Pesticides are both a boon and bane for civilization. Along with solving the problem of food crisis for the growing population it causes serious health hazards. The current study observes the histochemical effects with different doses of mancozeb widely used against diseases of field crops, fruits and ornamentals (Worthing, 1991) in the liver of albino mice. Though it has low acute toxicity; yet its breakdown product ethylene thiourea causes major toxicological concern and was found to have toxic effects in number of experimental animals. Three groups of Swiss albino mice were used wherein distilled water at 0.5 ml per mice per day orally was used in group I as control while the same volume of mancozeb dissolved in distilled water at a dose level of 4.2 mg/kg/bw and 6.4 mg/kg/bw were administered consecutively for 6 days a week for 4 weeks in group II and III respectively. The histochemical analysis of the samples revealed significant decrease in the intensity of stain for glucose content with severity in group III as compared to the control values. The results of the present work indicate marked alterations in the content of glucose in mancozeb exposed albino mice.
[L.K.Mudgal, S. Razia, A. Siddiqui (2015); Histochemical Effects of Carbohydrates on Liver of Mancozeb Induced Albino Mice Int. J. of Adv. Res. 3 (4). 0] (ISSN 2320-5407). www.journalijar.com
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