A CLINICAL STUDY ON THE EFFECT OF VATAGAJANKUSHA RASA IN GRIDHRASI.

Dr. Jibi Varghese T. 1 , Dr. Jonah S. 2 , Dr. Vaishali Deshpande 3 and Manna Mathew 4 . 1. Ph.D. Scholar, Department of Kayachikitsa, Parul Institute of Ayurveda, Parul University, Vadodara. 2. Professor , Department of Kayachikitsa,Rajiv Gandhi Ayurveda Medical College, Mahe. 3. Professor , Department of Kayachikitsa, Parul Institute of Ayurveda, Parul University. 4. P.G. Second Year, Department of Dravyaguna , Dr.D.Y.Patil College of Ayurveda &Research Centre, PimpriPune. ...................................................................................................................... Manuscript Info Abstract ......................... ........................................................................ Manuscript History Received: 10 September 2019 Final Accepted: 12 October 2019 Published: November 2019

Low backache is the fifth most common cause for all physician visits. The last few decades have shown that social and economical factors have great influence on the health. The present day life style and nature of work may be one of the causes for this malady. Gridhrasi is one such disease which is characterized by low backache with radiating pain up to the heel and causing the patient to walk like Gridhra, therefore been termed as Gridhrasi, which can be compared to that of Sciatica of contemporary Sciences 1,2 . Most of them neglect the preliminary stage of pain and refuse treatment but later, in advanced condition of the disease it becomes a must for them to seek medical advice. In allopathy, initially medications are advised and later patient may be suggested for surgical intervention. The cost is also not affordable by common man. So, a medicine, which relieves the pain, improves and restores functional ability, is the need for study. This is a Open label Comparative clinical study with pre-test and posttest design where in 40 patients suffering from Gridhrasi of either gender between the age group of 16 to 60 years were randomly selected and grouped into Group A and Group B. The patients in Group A were treated with Vatagajankusha Rasa 125mg bd with lukewarm water as Anupana Group B was given with Vatagajankusha Rasa 125mg bd with Manjistha kwatha 50 ml and Pippali choorna 3 gm bd as Anupana for 7 days. Results obtained were analyzed for the statistical significance by adapting paired and unpaired't' test. The study revealed that Group B ie, Vatagajankusha Rasa with the Anupana of Manjistha kwatha and Pippali choorna was found to be more effective in bringing symptomatic relief and improving functional ability in the patients of Gridhrasi.

…………………………………………………………………………………………………….... Introduction:-
Man is unique among his vertebrate cousins in stance of his upright stature. Other primates may enjoy the canopy of the tropical forest, sometimes climbing, sometimes semi-upright, but man alone is comfortable and confident with ISSN: 2320-5407 Int. J. Adv. Res. 7(11), 442-447 443 the upright bipedal posture. Spinal anatomy is a remarkable combination of strong bones, flexible ligaments and tendons, large muscles and highly sensitive nerves. The harmony of all these structures enables man to run with the pace of time. Man is taking the juxtaposition of strength, structure and flexibility of the spine for granted in everyday life.
Changing of life style of modern human being has created several disharmonies in his biological system. As the advancement of busy professional and social life, improper sitting posture in offices, factories, continuous and overexertion, jerky movements during traveling and sportsall these factors create undue pressure to the spinal cord and play an important role in producing low backache and pain radiating down the leg. Likewise, progressive disorders affecting the pelvis and nearer structures are also precipitating this condition. In this way, this disease is now becoming a significant threat to the working population. The disorder apparently seems to be non-serious but it cripples the patient and results in apprehension of social responsibilities and it also leads to draining of National Resource due to work hours lost, resulting into diminished production

Source of data
The patients who attended the OPD and IPD of S.D.M. Ayurveda Hospital, Udupi having the complaints of Low backache radiating to leg were screened. Among them 40 patients fulfilling the inclusion criteria of the present study were taken. A detailed history taking and physical examinations were carried out in these patients. Relevant data along with the elaborate assessment of Pain, Neurological deficit, Functional Ability & Functional Disability was registered in the designed case proforma.

Inclusion Criteria
The patients were taken for the present study as per the following inclusion criteria. 1. Patients with pratyatma lakshana of Gridhrasi. 2. Patients between the age group of 16 to 60 years. 3. Patients having positive physical signs of radicular pain/ Sciatica

Exclusion Criteria
The patients suffering from Gridhrasi caused due to the following were excluded from the study. 1. Neoplastic conditions of spine. 2. Trauma of spine 3. Infections of spine.

Investigations
Routine hematological investigations along with radiological investigations were carried out when ever found necessary.

Design
It is a single blind clinical study with pre test and post test design were in 40 patients diagnosed to have Gridhrasi fulfilling all the criteria for the study were selected randomly and was placed in a two groups A & B.

Intervention
The patients of Group A were treated with oral administration of Vatagajankusha Rasa 1 Bd with warm water and Group B were treated with Vatagajankusha Rasa with anupana as Manjishtha kwatha 50 ml and Pippali choorna 3 gram BD for the duration of 7 days.

Assessment criteria
Assessment was done initially before intervention of medicine and there after weekly for a period of 28 days. In the follow up period of 28days, the patients were assessed once in 7 days. Assessment was done by using the below mentioned

Method of preparation :
Firstly Rasasindhura is to be pulverized , later mixing in with all the Shuddha Bhasmas and drugs and it should be triturated with Mundi swarasa and Nirgundi swarasa . Then this is to be made into the form of vati and dried up in shade and preserved well in a glass bottle or a air tight tin.
446 Here in this study Vatagajankusha Rasa with luke warm water as anupana was given in Group A. The overall effect of the medication revealed 25% patients got cured as well as got best improvement in the symptoms respectively. 30% got moderate relief while 20% got mild relief from the symptoms. The second Group B, which was tried with Vatagajankusha Rasa and anupana of Manjishta kwatha and Pippali choorna, nearly 40% of the patients got cured and 25% each got best and moderate relief from the symptomolgy. 10% of the patients got mild improvement. Thus this present clinical study proved Vatagajankusha Rasa is effective in Gridhrasi.Though on comparing the efficacy of both the groups showed insignificant results yet ; Group B had good results compared to that of Group A since it had an added effect of the anupana yoga.