CEREBRAL VASOREACTIVITY TO CARBON DIOXIDE ASSESSED BY TRANSCRANIAL DOPPLER ULTRASOUND IN POST COVID-19 PATIENTS: A MOROCCAN COMPARATIVE STUDY

  • Department of Anesthesiology and Intensive Care– Military Teaching Hospital Mohammed V- Rabat-Morocco.
  • Faculty of Medicine and Pharmacy of Casablanca- HASSAN II University of Casablanca, Morocco.
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Background:COVID19 has been associated with multiple neurological manifestations, ranging from mild symptoms to severe cerebrovascular complications. The endothelium is a major target of SARS-CoV-2, and cerebral microvascular dysfunction may persist beyond the acute phase. The assessment of cerebral vasoreactivity(CVR) to carbon dioxide (CO2) using transcranial Doppler ultrasound (TCD) is a noninvasive method to detect subtle alterations in cerebral hemodynamics.

Objective: To evaluatecerebral vasoreactivity and the breath-holding index (BHI) in patients who recovered from moderate or severe COVID-19, compared with non COVID-19 controls.

Methods: A prospective observational study was conducted including 75 subjects: 50 post COVID-19 patients and 25 controls. Middle cerebral artery (MCA) flow velocities were recorded at rest and after a breath-holding test. CVR and BHI were calculated as the percentage change in mean flow velocity relative to baseline and to Breath Holding Time, respectively.

[Mohammed Rabi Andaloussi, Rida Touab, Khalil Mounir, Abdelhamid Jaafari , Mustapha Bensghir and Hicham Balkhi (2025); CEREBRAL VASOREACTIVITY TO CARBON DIOXIDE ASSESSED BY TRANSCRANIAL DOPPLER ULTRASOUND IN POST COVID-19 PATIENTS: A MOROCCAN COMPARATIVE STUDY Int. J. of Adv. Res. (Oct). 1552-1558] (ISSN 2320-5407). www.journalijar.com

RABI ANDALOUSSI MOHAMMED

Morocco

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