GC-MS STUDIES AND ANTIMICROBIAL ACTIVITY OF SUDANESE CAPSICUM ANNUM FIXED OIL.
- Sudan University of Science and Technology, Faculty of Science, Dept. of Chemistry.
- Bisha University , Faculty of Science.
- Omdurman Islamic University , Faculty of Pharmacy.
- UFA Pharmaceutical Industries, Khartoum
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The present study was designed to investigate the chemical constituents of Capsicum annum seed oil and to evaluate its potential antimicrobial activity. 27 components were detected by GC-MS analysis. Major constituents are: 9,12-octadecadienoic acid(56.57%) , , hexadecanoic acid(17.60%), 9-octadecenoic acid (5.62%) , methyl stearate(5.50%) and stigmasterol(2.37%) . Butylated hydroxytoluene, a potent antioxidant, was detected as a minor constituent(0.22%). The antibacterial activity of the oil was evaluated via cup plate agar diffusion assay against six standard human pathogens(Gram positive: Staphylococcus aureus and Bacillus subtilis; Gram negative : Escherichia coli and Pseudomonasa aeruginosa and the fungi Candida albicans and Aspergillus niger) . The oil showed different antimicrobial responses against test organisms. It was partially active against the fungus Candida albicans but significant activity against Staphylococcus aureus was observed.
[Abdel Karim, M., Nafesa, A.G., Weam M. K and Khadiga A. (2016); GC-MS STUDIES AND ANTIMICROBIAL ACTIVITY OF SUDANESE CAPSICUM ANNUM FIXED OIL. Int. J. of Adv. Res. 4 (Nov). 900-907] (ISSN 2320-5407). www.journalijar.com
