31Dec 2016
SYNTHESIS AND CHARACTERIZATION OF NOVEL AMINO CARBOXYLIC ACIDS.
- K. J. Somaiya College of Science and Commerce Vidyavihar (East), Mumbai-400077.
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A series of substituted amino carboxylic acids were synthesized by simple addition and reduction reactions using easily available reagents. Nitroalkanes such as nitromethane and nitroethane were reacted with aromatic aldehydes to give nitroalkenes which were further converted to substituted nitro esters by Michael addition reaction under mild conditions using KF supported alumina as a basic catalyst. These nitro esters were reduced to give substituted amino carboxylic acids using nickel chloride hexahydrate and sodium borohydride
[Bhanu Raman and Juned Munir Shaikh. (2016); SYNTHESIS AND CHARACTERIZATION OF NOVEL AMINO CARBOXYLIC ACIDS. Int. J. of Adv. Res. 4 (Dec). 2095-2100] (ISSN 2320-5407). www.journalijar.com
Dr. Bhanu Raman
K.J.Somaiya College of Science and Commerce, Vidyavihar (East), Mumbai-400077.
K.J.Somaiya College of Science and Commerce, Vidyavihar (East), Mumbai-400077.