NEW DEVELOPMENTS IN ANTICANCER ACTIVITIES OF IMIDAZOLE AND ITS DERIVATIVES.
- University Institute of Chemical Technology, North Maharashtra University, Jalgaon-425001.
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The heterocyclic compounds are well known for their diverse biological and clinical applications. The pharmacological importance of imidazole has been well established. It is constituents of important biomolecules such as histidine, biotin and alkaloids. Imidazole drugs are well-tolerated and are potentially active on number of targets, because of its polar and ionizable nature it will increase the solubility and bioavailability of the lead molecules. Moreover, nucleotides and imidazole derivatives are structural isosters so their interaction is responsible for delivering numerous biological activities and functions in living system. In view of these, the present review focus on the anticancer activities of imidazole nucleus.
[Rambhau P. Gore. (2016); NEW DEVELOPMENTS IN ANTICANCER ACTIVITIES OF IMIDAZOLE AND ITS DERIVATIVES. Int. J. of Adv. Res. 4 (Dec). 2256-2262] (ISSN 2320-5407). www.journalijar.com
University Institute of Chemical Technology, North Maharashtra University, Jalgaon-425001, (MS), India
