18Feb 2017

THE INHIBITORY EFFECT OF NEWLY SYNTHESISED GUAR EPOXY N-METHYL PIPERAZINE ON THE GROWTH OF PATHOGENIC BACTERIA AND FUNGI

  • Department of Chemistry, Jai Narain Vyas University, Jodhpur(Rajasthan),-342001, India.
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Guar based derivative was synthesised. The inhibitory activity of the newly synthesised derivative against pathogenic bacteria such E.coli, Klebseilla pnemoniae, Pseudomonas aeruginosa, Staphylococcus aureus and some strains of fungi such as C. kefyr, C. tropicalis, C. glabrata, C. auris, Geotricum candidum, Rhodoturula, C. parapsilosis, C. albicans was evaluated. The new resin was characterized by FT-IR, 1HNMR, XRD, Mass spectra and elemental analysis. Other resin characteristics like swelling, moisture content, bulk density and specific bulk volume were also studied. The antimicrobial activity was carried out by well diffusion method.


  1. https://en.wikipedia.org/wiki/Guar_gum
  2. Kays SE, Morris JB, Kim Y(2006):Total and soluble dietary fiber variation in cyamopsistetragonoloba (L.) Taub. (Guar) genotypes.J Food Quality,29:383–391.
  3. Singh A.V, Sharma N(2011):Characterisation and applications of synthesised cation exchanger guar gum sulphonic acid (GSA) resin for removaland recovery of toxic metal ions from industrial wastewater (Available on website http://www.wrc.org.za)
  4. Ventola C.L.(2015):The antibiotic resistance crisis: Part 1: Causes and threats. P T, 40, 277–283.
  5. ,Tiller J.C.(2012): Antimicrobial polymers in solution and on surfaces: Overview and functionalprinciples. Polymers, 4, 46–71.
  6. Muñoz-Bonilla A., Fernández-García M.(2012): Polymeric materials with antimicrobial activity. Prog. Polym. Sci., 37, 281–339.
  7. Kenawy E.R., Worley S.D., Broughton R.(2007): The chemistry and applications of antimicrobial polymers: A state-of-the-art review,Biomacromolecules, 8, 1359–1384.
  8. Jain A., Duvvuri L.S., Fara S., Beyth N., Domb A.J., Khan W(2014): Antimicrobial polymers,
  9. Healthc. Mater, 3, 1969–1985.
  10. Daljit S.A.,Jasleen K (1999):Int J. Antimicro. Agents, 2, 257-262.
  11. Adegboye M.F.,Babalola O.O., and Akinpelu D.A. (2012): Issues of resistance of pathogens to antimicrobial agents,ScientificResearch Essays, vol. 7, no. 41, pp. 3468–3478.
  12. Worley S.D., Broughton, Roy (2007): American Chemical Society, 8(5), 1359-1364.
  13. Xue Y., Xiao H., Zhang Y.(2015): Antimicrobial polymeric materials with quaternary ammonium and phosphoniumsalts,Int. J. Mol. Sci., 16, 3626–3655.
  14. Leceta I., Guerrero P., Ibarburu I., Due˜nas M.T., and K. de la Caba (2013): Characterization and antimicrobial analysis of chitosan based films,Journal of Food Engineering, vol. 116, no. 4,pp. 889–899.

[Richa Chauhan and Sangeeta Loonker (2017); THE INHIBITORY EFFECT OF NEWLY SYNTHESISED GUAR EPOXY N-METHYL PIPERAZINE ON THE GROWTH OF PATHOGENIC BACTERIA AND FUNGI Int. J. of Adv. Res. 5 (Feb). 333-341] (ISSN 2320-5407). www.journalijar.com


Richa Chauhan
Jai Narain Vyas University,Jodhpur (Rajasthan)

DOI:


Article DOI: 10.21474/IJAR01/3153      
DOI URL: http://dx.doi.org/10.21474/IJAR01/3153