22Apr 2017

DIAGNOSTIC USEFULNESS OF PROCALCITONIN AND C-REACTIVE PROTEIN IN GRAM NEGATIVE BACTERIAL INFECTIONS.

  • Senior Specialist Biomedical Scientist, Blood Sciences Department, Frimley Park Hospital NHS Trust, Camberley, Surrey, GU 16 7UJ ,UK.
  • Research Scholar, Department of Biochemistry, VelsUniveristy, Pallavaram, Chennai ? 600 117. Tamil Nadu, India.
  • Director of Laboratory Services & Consultant Biochemist, Techmed Health Care & Diagnostic Pvt Ltd. Siva Building, Krishna Street, Opp. Joyalukas, North Usman Road, T.Nagar, Chennai 600 017.
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Any biomarker used to substantiate bacterial infections should aid in the rapid diagnosis, initiation of treatment and during prognosis monitoring. As of now a wide range of biomarkers have been established and more researches are being done in this field. Markers such as ESR, C-Reactive Protein, Procalcitonin and Leucocyte count have been extensively studied for a wide range of bacterial infections. However, studies related to biomarkers, C-Reactive Protein and Procalcitonin have been found to be very useful in early diagnosis, treatment and monitoring the effect of antibiotic treatment, Both the above markers were found to be very useful in the diagnosis of gram negative bacterial infection compared to other type of infections such as by gram positive. Moreover, both these markers are found to be useful in infective fever, meningitis, sepsis, critical care patients, graft acceptance/rejection and in pneumonia. This review article present the various research findings related to the clinical usefulness of these biomarkers in the diagnosis of infections caused by gram negative bacteria.

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[Rajeswari S and Swaminathan S. (2017); DIAGNOSTIC USEFULNESS OF PROCALCITONIN AND C-REACTIVE PROTEIN IN GRAM NEGATIVE BACTERIAL INFECTIONS. Int. J. of Adv. Res. 5 (Apr). 321-329] (ISSN 2320-5407). www.journalijar.com

Dr. S. Swaminathan
Director of Laboratory Services & Consultant Biochemist, Techmed Health Centre & Diagnostic (P) Ltd., 01, Siva Building, Krishna Street, Off North Usman Road, T.Nagar, Chennai - 600017

DOI:

Article DOI: 10.21474/IJAR01/3814      
DOI URL: http://dx.doi.org/10.21474/IJAR01/3814

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