17Jul 2017

QUALITY OF LIFE IN PATIENTS WITH MIGRAINE, RECEIVING A HOMEOPATHIC TREATMENT (ARNICA MONTANA LINN.) - A SHORT TERM PROSPECTIVE STUDY.

  • B.K.Mody Government Pharmacy College, Rajkot,Gujarat, India.
  • Meghani Homeopathic Hospital, Rajkot, Gujarat, India.
Crossref Cited-by Linking logo
  • Abstract
  • Keywords
  • References
  • Cite This Article as
  • Corresponding Author

Background: Migraine is chronic neurovascular disorder which affects the quality of life. Design: It was single centric, parallel, randomised, single blinded, placebo-controlled clinical trial conducted on patients of migraine. Experimental work: 130 patients were enrolled in the study. By randomised technique 65 patients were placed in placebo group and 65 patients were placed in treatment group.The study was conducted for 4 months at Meghani Homeopathy Hospital, Rajkot. Demographic data, Improvement in Quality of Life in the two groups were compared. Statistical analysis used: Based on the normality of data, unpaired t test or Mann Whitney U test was used for comparison of changes in SF-36 scores for Quality of Life. Result and discussion: Female in gender, working age of people and common migraine (unilateral side) was found to most prevalent in Rajkot region. Comparison of 0 and 120 days showed marked decrease in frequency, duration and intensity of attack significantly. SF-36 scale showed significant increase in treatment group after 120th day treatment from placebo group. These scales differences were statistical significant (P <0.05) except the mental health as compared to placebo group. PCS (Physical Component Summary) and MCS (Mental Component Summary) both were found to increase in treatment group 48.49?0.68 and 46.18?0.685 as compared to placebo group 30.3?1.02 and 42.60?0.69(120 days). The increase in PCS and MCS was significant statistically (P < 0.05). Conclusion: Arnica- 30c a homeopathic formulation at the end of 120 days was found to improve Quality of Life in patients of migraine.

  1. Muscari- Tomaioli G, Allegri F, Miali E, Pomposelli R, Tubia P, Targhetta A, Castellini M, Bellavite P.," Observational study of quality of life in patients with headache, receiving homeopathic treatment"Br Homeopath J., 2001, 90,pp. 189-197.
  2. Eiware John et al., ?MOS 36-Item Short-Form Health Survey (SF-36)?,Medical Care .,June 1992, vol.30,no.6,pp.473-483.
  3. Mahajan BK, Methods in Biostatistics for Medical students and Research Workers, 7th,2012,pp.84-85.
  4. Ghooi B. Ravindra, Itkar C. Sachin, Essentials of Clinical Research, Nirali Prakashan,2010,pp.36-66.
  5. Rang H.P., Dale,M.M.,Ritter JM., Flower R.J.,Henderson.G., Rang and Dale?s Pharmacology;6th Edn; Elsevier Churchill living stone,2007,pp-195-196.
  6. Boericke, William., Boericke, Oscar E.,Homeopathic Materia Medica,1927 ,5th Edn;1963.
  7. Tommaso Iannitti, Julio Cesar Morales-Medina,Paolo Bellavite,Valentina Rottigni, Beniamino Palmieri,, ?Effectiveness and safety of Arnica montana in post surgical setting, pain and inflammation?, American Journal of Thearapeutics, 2016, vol-14, pp187-193.
  8. RahulRathod,MirzaSirajBaig,P.N.Khandelwal,S.G.Kulkarni,P.R.Grade,SamiraSiddiqui,?Results of a single blind, randomized, placebo-controlled clinical trial to study the effect ofintravenous l-carnitine supplementation on health-related quality of life in indian patients on maintenance hemodialysis?, Indian J Med Sci.,vol-6,April 2006,pp143-153.

[Debdoot Basu, Devang B. Sheth, Bhagyashree Patel and N. J. Meghani. (2017); QUALITY OF LIFE IN PATIENTS WITH MIGRAINE, RECEIVING A HOMEOPATHIC TREATMENT (ARNICA MONTANA LINN.) - A SHORT TERM PROSPECTIVE STUDY. Int. J. of Adv. Res. 5 (Jul). 289-300] (ISSN 2320-5407). www.journalijar.com

Debdoot Basu
M.Pharm (Pharmacology)

DOI:

Article DOI: 10.21474/IJAR01/4717      
DOI URL: http://dx.doi.org/10.21474/IJAR01/4717

Download Full Paper

Download PDF No. of Downloads: 83 | No. of Views: 370