18Sep 2017

MARINE BACTERIA AND FUNGI AS SOURCES FOR BIOACTIVE COMPOUNDS: PRESENT STATUS AND FUTURE TRENDS.

  • Department of Zoology, Faculty of Applied Sciences, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.
Crossref Cited-by Linking logo
  • Abstract
  • Keywords
  • References
  • Cite This Article as
  • Corresponding Author

Marine organisms undergo a vast range of chemical and physical conditions in the marine environment, thus a high diversity is reported in the bioactive compounds they produce. With the development of marine biotechnology, a considerable number of researches are focused on marine bacteria and fungi-derived bioactive compounds. As a result, marine bacteria and fungi are ranked on the top of the hierarchy of all organisms, as they are responsible for producing a wide range of bioactive secondary metabolites with potential pharmaceutical applications. Thus, they have the potential to provide future drugs against important diseases, such as cancer, a range of viral diseases, malaria, and inflammations. This review aims at describing some of the most highly cited reviews of the last decade on marine bacteria and fungi -derived bioactive compounds and the most promising substances extracted and isolated from these for pharmaceutical applications.

  1. Arena, A., Gugliandolo, C., Stassi, G., Pavone, B., Iannello, D., Bisignano, G., & Maugeri, T. L. (2009). An exopolysaccharide produced by Geobacillus thermodenitrificans strain B3-72: antiviral activity on immunocompetent cells.Immunology letters,?123(2), 132-137.
  2. Barbachyn, M. R., & Ford, C. W. (2003). Oxazolidinone structure?activity relationships leading to linezolid.Angewandte Chemie International Edition,?42(18), 2010-2023.
  3. Bhatnagar, I., & Kim, S. K. (2010). Immense essence of excellence: marine microbial bioactive compounds.Marine drugs,?8(10), 2673-2701.
  4. Charan, R.D., Garson, M.J., Brereton, I.M., Willis, A.C., Hooper, J.N.A., 1996. Haliclonacylamins A and B: cytotoxic alkaloids from the tropical marine sponges Haliclona sp. Tetrahedron 52, 9111 ? 9120
  5. Cragg, G. M., & Newman, D. J. (2013). Natural products: a continuing source of novel drug leads.Biochimica et Biophysica Acta (BBA)-General Subjects,?1830(6), 3670-3695.
  6. Debbab, A., Aly, A. H., Lin, W. H., & Proksch, P. (2010). Bioactive compounds from marine bacteria and fungi.Microbial biotechnology,?3(5), 544-563.
  7. Egan, S., James, S., Holmstr?m, C., & Kjelleberg, S. (2002). Correlation between pigmentation and antifouling compounds produced by Pseudoalteromonas tunicata.Environmental Microbiology,?4(8), 433-442.
  8. Jensen, P. R., Gontang, E., Mafnas, C., Mincer, T. J., & Fenical, W. (2005). Culturable marine actinomycete diversity from tropical Pacific Ocean sediments.Environmental microbiology,?7(7), 1039-1048.
  9. Jha, R. K., & Zi-Rong, X. (2004). Biomedical compounds from marine organisms.Marine drugs,?2(3), 123-146.
  10. Maldonado, L. A., Stach, J. E., Pathom-aree, W., Ward, A. C., Bull, A. T., & Goodfellow, M. (2005). Diversity of cultivable actinobacteria in geographically widespread marine sediments.Antonie Van Leeuwenhoek,?87(1), 11-18.
  11. Oldfield, C., Wood, N.T., Gilbert, S.C., Murray, F.D., and Faure, F.R. 1998. Desulphurisation of benzothiophene and dibenzothiophene by actinomycete organisms belonging to the genus Rhodococcus, and related taxa. Antonie Van Leeuwenhoek. 74: 119?132.
  12. Romanenko, L. A., Uchino, M., Kalinovskaya, N. I., & Mikhailov, V. V. (2008). Isolation, phylogenetic analysis and screening of marine mollusc-associated bacteria for antimicrobial, hemolytic and surface activities.Microbiological research,?163(6), 633-644.
  13. Schmitt, T. M., Lindquist, N., & Hay, M. E. (1998). Seaweed secondary metabolites as antifoulants: effects of Dictyota spp. diterpenes on survivorship, settlement, and development of marine invertebrate larvae.Chemoecology,?8(3), 125-131
  14. Strohl, W. R. (2004). Antimicrobials. InMicrobial diversity and bioprospecting?(pp. 336-355). American Society of Microbiology.
  15. Zhang, L., An, R., Wang, J., Sun, N., Zhang, S., Hu, J., & Kuai, J. (2005). Exploring novel bioactive compounds from marine microbes.Current opinion in microbiology,?8(3), 276-281.
  16. Berdy,J (2005). Bioactive microbial metabolites. Journal of Antibiotics, 58(1): 1?26
  17. Lam, K. S. (2006). Discovery of novel metabolites from marine actinomycetes. Current opinion in microbiology,Elsivier (2006, 9:245?251)
  18. DChauhan,D, Hideshima,T and? Anderson, K.C. (2006). A novel proteasome inhibitor NPI0052 as an anticancer therapy. British Journal of? Cancer ; 95(8): 961?965.
  19. Maldonado,L.A., James E.M. Stach , Wasu Pathom-aree , Alan C. Ward , Alan T. B and Michael G (2005).Diversity of cultivable actinobacteria in geographically widespread marine sediments, Antonie van Leeuwenhoek? 87:11?18.
  20. Gallo, M.L., Seldes, A.M. and Cabrea, G.M. (2003). Antibiotic long-chain A,B-unsaturated Aldehydes from the culture of the marine fungus Cladosporium Biochemicals systematic and Ecology.32(6),545-551)
  21. Newman, D. J., & Hill, R. T. (2006). New drugs from marine microbes: the tide is turning.Journal of Industrial Microbiology and Biotechnology,?33(7), 539-544.
  22. Kjer, J., Debbab, A., Aly, A. H., & Proksch, P. (2010). Methods for isolation of marine-derived endophytic fungi and their bioactive secondary products.Nature protocols,?5(3), 479.
  23. Du, Z., Li, H., & Gu, T. (2007). A state of the art review on microbial fuel cells: a promising technology for wastewater treatment and bioenergy.Biotechnology advances,?25(5), 464-482.
  24. Mizuno, C. M., Rodriguez-Valera, F., Kimes, N. E., & Ghai, R. (2013). Expanding the marine virosphere using metagenomics.PLoS genetics,?9(12), e1003987.
  25. Li, Z. Y., & Liu, Y. (2006). Marine sponge Craniella austrialiensis‐associated bacterial diversity revelation based on 16S rDNA library and biologically active Actinomycetes screening, phylogenetic analysis.Letters in applied microbiology,?43(4), 410-416.
  26. Li, Z. Y., He, L. M., Wu, J., & Jiang, Q. (2006). Bacterial community diversity associated with four marine sponges from the South China Sea based on 16S rDNA-DGGE fingerprinting.Journal of Experimental Marine Biology and Ecology,?329(1), 75-85.
  27. Xu, L., Meng, W., Cao, C., Wang, J., Shan, W., & Wang, Q. (2015). Antibacterial and antifungal compounds from marine fungi.Marine drugs,?13(6), 3479-3513.
  28. Lukassen, M. B., Saei, W., Sondergaard, T. E., Tamminen, A., Kumar, A., Kempken, F., ... & S?rensen, J. L. (2015). Identification of the scopularide biosynthetic gene cluster in Scopulariopsis brevicaulis.Marine drugs,?13(7), 4331-4343.

[Varuni K Gunathilake (2017); MARINE BACTERIA AND FUNGI AS SOURCES FOR BIOACTIVE COMPOUNDS: PRESENT STATUS AND FUTURE TRENDS. Int. J. of Adv. Res. 5 (Sep). 610-614] (ISSN 2320-5407). www.journalijar.com

Varuni K Gunathilake
Department of Zoology, Faculty of Applied Sciences, University of Sri Jayewardenepura,Gangodawila ,Nugegoda, Sri Lanka

DOI:

Article DOI: 10.21474/IJAR01/5367      
DOI URL: http://dx.doi.org/10.21474/IJAR01/5367

Download Full Paper

Download PDF No. of Downloads: 115 | No. of Views: 287