01Jan 2017

Diagnosis of Giardia lamblia by Detection of Parasite- Anti-Giardia Antibodies in Children

Abstract


BACKGROUND : Giardiasis is a major diarrhea disease found throughout the world. The flagellate protozoan Giardia lamblia, its causative agent, is the most commonly identified parasite isolated worldwide. OBJECTIVES: This study was to measuring specific serum anti-Girdia( IgM and IgA) antibodies by ELISA assay. SUBJECTS AND METHODS: Blood samples were collected from Sixty four (64 )children with gastrointestinal problems, at AL-Imamain AL-Kadimain medical city from 1st March 2014 to 30th June 2014 at pediatric out patients clinic, of both sexes, their age range from 7 months to 7 years, Addison healthy control include twenty seven(27) children (age matched). The serum sample was used for detection of human anti-Giardia lamblia IgM and IgA antibody by ELISA test. RESULTS: The study showed the mean age group was (3.18±0.28), but there is highly significant difference for B.W and Hb in the study groups(P=<0.001). males predominance among patients about (56.5%), while (43.8 %) were females. elevated levels of IgM antibodies 52(57.1%) total positive, that highly significant differences (p<0.001), also highly percentage borderline for IgA antibodies 40(44.0%) significant differences (P <0.002). CONCLUSION: There is higher serum IgM antibodies level in Giardiasis patients who have active disease. Serum IgA antibodies level is higher borderline which may play important role for protection.


Cite This Article as:


[Abdul- Kareem Mohammed Ali, Huda Al-marsome and Nadia Hikmat Mohammed (2015); Diagnosis of Giardia lamblia by Detection of Parasite- Anti-Giardia Antibodies in Children Int. J. of Adv. Res. 3 (2). 0] (ISSN 2320-5407). www.journalijar.com


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