PHYTOCHEMICAL CONSTITUENTS AND ANTIMICROBIAL ACTIVITIES OF THE ROOT BARK EXTRACTS OF Massularia acuminata spp.
- Department of Science Laboratory Technology, Federal Polytechnic, Damaturu, Nigeria. Chemistry programme, Abubakar Tafawa Balewa University, Bauchi, Nigeria.
- Biological Sciences Programme, Tafawa Balewa University, Bauchi, Nigeria.
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The root bark extracts of Massularia acuminata from Akwa Ibom State, Nigeria, (locally known as “okok edi”) have been investigated for its phytochemical constituents and antimicrobial activities. Air dried pulverized root bark of the plant part was sequentially solvent extracted with hexane, chloroform, ethyl acetate, acetone, ethanol and methanol. The phytochemical screening of the extracts show the presence of alkaloids, anthraquinones, saponins, phlobatannins, cardiac glycosides, tannins, terpenoids, steroids, flavonoids and resins, but not across all the extracts. Ethyl acetate, acetone, ethanol and methanol extracts were assayed for their antimicrobial activities and all were found to be active against the clinical isolates, Salmonella spp. Staphylococcus aureus, Eschurichia coli, Aspergillus nigger and Candida albicans but at varied level. The presence of some phytochemicals with known pharmacological effects in the plant part extracts and their antimicrobial activities justify the traditional use of the plant part for medicinal purpose.
[U. S. Ukekpe, H. M. Adamu, E.O. Ekanem and A. A. Saleh. (2015); PHYTOCHEMICAL CONSTITUENTS AND ANTIMICROBIAL ACTIVITIES OF THE ROOT BARK EXTRACTS OF Massularia acuminata spp. Int. J. of Adv. Res. 3 (Aug). 557-565] (ISSN 2320-5407). www.journalijar.com
