20Jan 2017

PRETERM LABOUR: A STUDY OF ETIOLOGICAL RISKFACTORS AND PERINATAL OUTCOME.

  • Associate Professor, NDMC Medical College and Hindu Rao Hospital, Delhi.
  • Senior Resident, NDMC Medical College and Hindu Rao Hospital, Delhi.
  • Professor, NDMC Medical College and Hindu Rao Hospital, Delhi.
Crossref Cited-by Linking logo
  • Abstract
  • Keywords
  • References
  • Cite This Article as
  • Corresponding Author

Objective: To study the causes associated with preterm labour and the perinatal outcome in preterm labour. Methods: This prospective observational study was conducted in the department of obstetrics and gynaecology NDMC Medical College and Hindu Rao Hospital over a period of 6 months (Jan to June 2016). All patients presented with preterm labour, preterm premature rupture of membrane and with conditions where labour was iatrogenicallyinduced prematurely were included in the study. All the patients were divided into four groups depending upon the gestational age – less than 28 weeks, 28 to 31 weeks, 32 to 34 weeks and more than 34 weeks. Risk factors and the perinatal outcome were analyzed. Results: Out of 4382 patients delivered 946 were preterm delivery (21.5%).54 out of 946 preterm deliveries had come with intrauterine death. The commonest risk factor of preterm delivery was preterm premature rupture of membrane followed by infection, anemia, preeclampsia and abruption. 73.2% of patients went into spontaneous preterm labour and 26.8% had caesarean section. Maximum perinatal complications and death were seen in group with gestational age less than 28 weeks. Conclusions: The most common associated cause for preterm birth was preterm premature rupture of membrane. Perinatal outcome improves with gestational age. All preterm deliveries should be conducted in tertiarycare hospital where better neonatal care is available.


  1. Mc CormiekMC.(1985): The contribution of low birth weight to infant mortality and childhood morbidity. N Engl J Med., 312: 82-90
  2. Beck S, WojdylaD, Say L, et al. (2010): The worldwide incidence of preterm births, a systematic review of maternal mortality & morbidity. Bulletin of world health org 88:31.38
  3. World Health Organization (2006): Neonatal and perinatal mortality: country,regional and global estimates. WHO, Geneva
  4. Tucker JM, Goldenberg, RL, Davis RO, et al. (1991): Etiologies of preterm birth in an indigent population: Is prevention a logical expectation. Obstet Gynecol., 77: 343-347
  5. Raju TNK.(2006): Epidermiology of late (near-term) preterm birth. Clin perinatal., 33:751-763
  6. Preterm labour in Textbook of obstetrics by D.C Dutta 6th (2004): Published by new central book agency, Calcutta. Page 314-315
  7. Bangal VB, Shinde KK, Gayatri KK, Patil NA. (2012): A study of risk factors and perinatal outcome in preterm labour at tertiary care hospital. International journal of Biomedical research.,3(3):147-150
  8. Devi PK, Krishna Menon MK, Bhasker Rao K. (1980): Post Graduate Obstetrics and Gynaecology, 3rd, Published by orient Longman ltd Madras. Page 204-209
  9. P, Jain P.C and Prasad B.G. (1970) Environmental factors in preterm labour. J.Obstetrics and Gynae India.,20: 728.
  10. Preterm birth trends in Greece, (1980-2008): A rising concern. BaroutisG, MousiolisA, Mesogitis S, Costalos C, Antsaklis A. ActaobstetGynecol Scand. 2013’29.
  11. Singh M, Khare UN and Bhargava SK. Third International seminar on Maternal Mortality, Perinatal Mortality and Sterilisation, 3rd -5th October 1980, New Delhi
  12. Leitich H, Bonder-Adler B, Brunbauer M, Kaider A, Egarter C, Husslein P. (2003): Bacterial vaginosis as a risk factor for preterm delivery: A meta-analysis Am J Obstet Gynecol.,189(1): 139-147
  13. Morency AM, Bujold E. (2007):The effect of second trimester antibiotic therapy on the rate of preterm birth, J ObstetGynecol Can., 29(1):35-44
  14. BerghellaU, Baxter JK, Hendrix NW. Cervical assessment by ultrasound for preventing preterm delivery. Cochrane database of systematic reviews 2009; Issue 3. Art.no; CD 007235
  15. American college of Obstetrician and Gynaecologists. Antenatal corticosteroid therapy for fatal maturation. Committee opinion no 419. (2008): Obstet Gynecol., 112: 963- 965.
  16. American College of obstetrician and gynaecologists. (2008): Antenatal corticosteroid therapy for fetal maturation. COG committees opinion no 402. Obstet Gynecol., 111: 805.

[Shilpa Dhingra, Bhumika Shukla and Sudha Salhan. (2017); PRETERM LABOUR: A STUDY OF ETIOLOGICAL RISKFACTORS AND PERINATAL OUTCOME. Int. J. of Adv. Res. 5 (Jan). 703-707] (ISSN 2320-5407). www.journalijar.com


SHILPA DHINGRA
ASSOCIATE PROFESSOR, Obstetrics & Gynaecology Deptt, NDMC Medical College & Hindu Rao Hospital, Delhi

DOI:


Article DOI: 10.21474/IJAR01/2802      
DOI URL: http://dx.doi.org/10.21474/IJAR01/2802