20Jan 2017


  • Faculty of Science, Cairo University, Department of Chemistry, Lab of Biochemistry.
  • Faculty of Science, Cairo University, Department of Chemistry.
  • NationalDiabetes and Endocrinology Institute.
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Purpose: This work has been carried out to evaluate the arginase activity andlactoferrin (LF) level as biochemical markers in type 2 diabetic Egyptian. Subjects and Methods: The present study consisted of 84 patients classified into threegroups: Uncontrolled diabetic patients [G1], Control diabetic patients [G2], Normal healthy subjects [G3]. Lactoferrin concentration was measured using ELISA technique. Arginase andother biochemical parameters were measured by using Jenway 6105 uv/vis spectrophotometer. Finally, all the results were statistically analyzed andcompared with normal subjects [G3]. Results: The mean sera value of both arginase and LF was found to beelevated in uncontrolled type 2 diabeticpatient group[G1] and controlled type 2 diabetic patientgroup[G2] compared to normal healthygroup [G3]. Conclusion: Both arginase and LF are considered as good biomarkers fordiagnosis of type 2 diabetes and for detection of the best and most effectivemethod for the treatment.

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[Mohamed A. El-Desouky, Sanaa Osman, Nashwa M. Shams Eldin and IbrahimEmaraa. (2017); ARGINASE ENZYME ACTIVITY AND LACTOFERRIN PROTEIN CONCENTRATION IN EGYPTIAN DIABETIC PATIENTS. Int. J. of Adv. Res. 5 (1). 1518-1523] (ISSN 2320-5407). www.journalijar.com

Nashwa M. Shams Eldin
Faculty of Science, Cairo University, Department of Chemistry, Lab of Biochemistry


Article DOI: 10.21474/IJAR01/2915       DOI URL: http://dx.doi.org/10.21474/IJAR01/2915

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