Evaluation of anti-Helicobacter pylori IgG level in the serum of patients with Rheumatoid arthritis

Abstract: Rheumatoid arthritis is an inflammatory chronic disease with an autoimmune pathogenesis. To determine the role of Helicobacter pylori as a trigger agent, twenty five patients with rheumatoid arthritis of ages (15-47) years have been investigated and compared with twenty healthy individuals. All the studied groups were carried out to measure the rheumatoid arthritis (RA) IgM, anti-CCP antibody IgG and IgA by ELISA test and by measured anti-IgG antibody level of H. pylori by using ELISA and IFAT techniques. The present study showed significant differences (P< 0.05) of anti-H. Pylori in sera of RA patients than control group, this lead to suggest that H. pylori had a role in pathogenesis of RA.

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[Dunya F. Salloom, Rana S. Abood, Ali H. Abbas (2014); Evaluation of anti-Helicobacter pylori IgG level in the serum of patients with Rheumatoid arthritis Int. J. of Adv. Res. 2 (4). 0] (ISSN 2320-5407). www.journalijar.com

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