31Jan 2017

EFFECT OF THE METHANOLIC LEAF EXTRACT OF BOSWELLIA DALZIELII HUTCH ON THE LIVER INTEGRITY OF SELENITE-INDUCED CATARACT PUPS.

  • Institutional Affiliation: Department of Biochemistry, Faculty of Science, University of Port- Harcourt, P.M.B 5323, Port-Harcourt, Nigeria.
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The effect of Boswellia dalzielii Hutch extract on the liver integrity of selenite-induced cataract pups was investigated. Nine groups of five pups each were used for this study. Group 1 received normal saline, groups 2 to 9 received 30µmol/kg BW of sodium selenite. Eight days post administration of selenite, the presence of cataract was confirmed with the aid of an ophthalmoscope, after which the treatment commenced and lasted for 28 days. The extract significantly (p<0.05) lowered alkaline phosphatase activity and total bilirubin concentration. The obtained results infer that B. dalzielii Hutch leaf extract had no harmful effect on the liver integrity of selenite-induced cataract pups.


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[Divine A. Onobrudu, Eugene N. Onyeike and Jude C. Ikewuchi. (2017); EFFECT OF THE METHANOLIC LEAF EXTRACT OF BOSWELLIA DALZIELII HUTCH ON THE LIVER INTEGRITY OF SELENITE-INDUCED CATARACT PUPS. Int. J. of Adv. Res. 5 (Jan). 2600-2604] (ISSN 2320-5407). www.journalijar.com


DIVINE A. ONOBRUDU
Institutional Affiliation: Department of Biochemistry, Faculty of Science, University of Port- Harcourt, P.M.B 5323, Port Harcourt, Nigeria.

DOI:


Article DOI: 10.21474/IJAR01/3049      
DOI URL: http://dx.doi.org/10.21474/IJAR01/3049