17Jul 2017

A STUDY OF EVALUATION OF AGNOR IN SALIVARY GLAND TUMORS.

  • Assistant Professor, Department of Oral Pathology & Microbiology, Government dental college and Hospital, Mumbai.
  • Dean and Professor, Department of Oral Pathology & Microbiology, Government dental college and Hospital, Nagpur.
  • Professor, Department of Oral Pathology & Microbiology, Government dental college and Hospital, Nagpur.
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Objective: The aim of this study was to evaluate the application of AgNOR in various benign and malignant salivary gland tumors by quantitative analysis of AgNOR and to determine its relation to histopathologic findings. As well as compare with normal salivary gland tissue as a control. Study design: Forty- cases of benign and malignant salivary gland tumors were retrieved and the mean AgNOR count was calculated for all cases. Results: Mean AgNOR counts were 1.72+_0.29, 2.76+_0.75, and 1.3+_ 0.86 in benign, malignant and normal salivary gland tissue respectively .Unpaired ?t? test and ANOVA test was applied to test significance. A significant difference was observed in the mean AgNOR counts among the3 groups (P < 0.001). But among benign and malignant group there was no significant difference. Conclusion:It can be suggested that the AgNOR technique can be applied on routine histological samples to assess the growth potential of salivary gland tumors. However, its prognostic value should be validated with clinical studies and survival analyses.

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[Manisha Aba Sardar, V. K. Hazarey and S. M. Ganvir. (2017); A STUDY OF EVALUATION OF AGNOR IN SALIVARY GLAND TUMORS. Int. J. of Adv. Res. 5 (Jul). 347-359] (ISSN 2320-5407). www.journalijar.com

DR. MANISHA A. SARDAR
GOVERNMENT DENTAL COLLEGE AND HOSPITAL, MUMBAI

DOI:

Article DOI: 10.21474/IJAR01/4726      
DOI URL: http://dx.doi.org/10.21474/IJAR01/4726

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