HEPATITE C ET DIABETE TYPE II.

Type 2 diabetes and hepatitis C virus (HCV) infection are two of the most important problems of public health in the world. A relationship between these two diseases has been discussed by several teams in the literature. However, risk factors for this association remain unsolved. The main purpose of our study was to estimate the prevalence of HCV in the population with type 2 diabetes. The present study is an observational descriptive transversal study conducted between June 2012 and December 2012 in the department of Endocrinology- Diabetology and Metabolic Diseases in the Military Hospital Avicenna of Marrakesh. After explaining the objectives of our study to patients, who had to express by writing their consent, we collected information about the demographic data, socio-economic data, family antecedents of type 2 diabetes and risk factors for HCV infection. Then, all patients underwent a complete clinical examination. The search for anti-VHC Antibodies, the assessment of liver function and glycemic balance were performed on all patients. Research and quantification of viral RNA were routinely done to patients with anti-VHC antibodies. Nine patients with type 2 diabetes in 200 (4,5%) were found to be infected with HCV. The mean age of patients was 55 years with a sex ratio of 1,08. The majority of patients had an unbalanced type 2 diabetes, with a mean age of 6 and a half years and a mean HbA1c of 8,22%. Genotype 1 was the most frequent (77,8%). A positive correlation was observed between the prevalence of HCV infection and type 2 diabetes in our study population. This increase in prevalence is an important factor, enabling precocious detection and better management of VHC infection within patients with type 2 diabetes.