In-vitro Evaluation of Antimicrobial Activity of Ganoderma lucidum

Abstract: Ganoderma sp. provides bioactive compounds that claim to posses antibacterial activity. The aim of this research is to know antimicrobial activity of various extract of Ganoderma lucidum. Fruiting bodies of Ganoderma lucidum. were extracted by maceration method using 50 % aceton, 50 % ethanol, methanol and boiling water, The antimicrobial activity of various solvent extracts (50µg/ml) of Ganoderma lucidum was tested against six species of bacteria: Escherichia coli (MTCC-443), Staphylococcus aureus (MTCC-187), Bacillus subilis (MTCC-1789) Salmonella typhi (MTCC-531) and Pseudomonas aeruginosa (MTCC-779), Vibrio cholera (MTCC 1068). Acetone extract exhibited maximum antibacterial activity (31.60±0.10), The acetone extract (1000mg/ml) possess strong antifungal activity against 5 fungal strains which were tested by using poisoned food technique The strains used for antifungal activity consisted of Aspergillus niger FCN#34, Curvularia lunata FCN #12, Fusarium oxysporum FCN #80 ,Alternaria alternata FCN #15 Drashelaria sp. FCN #31.

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[Jaya Singh, Saurabh Gupta, Sonam Malviya, and Bharti Ahrwar (2014); In-vitro Evaluation of Antimicrobial Activity of Ganoderma lucidum Int. J. of Adv. Res. 2 (6). 0] (ISSN 2320-5407).

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