17Jul 2017

CYTOCHROME B AND BETA-FIBRINOGEN IMPLICATION IN THE GENETIC EVOLUTION OF BREAST MALIGNANT TUMOUR IN SENEGALESE WOMEN

  • Departement de BiologieAnimale, Faculte des Sciences et Techniques, Universit? C.A. Diop, B.P. 5005 Dakar, Senegal.
  • Centre de Biologie des Populations AnimalesSah?loSoudaniennes (BIOPASS), UMR 022, Institut de Recherche pour le d?veloppement, IRD/Bel-Air, Senegal.
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The International Cancer Centre (CIRC) stated that there is an important increase of breast cancer throughout the world. In Senegal, breast cancer is known as the malicious tumour more developed among women. From thirty (30) Senegalese women were tested, the notice is that a mitochondrial (Cytochrome b) and a nuclear (Beta-fibrinogen) gene evaluated the level of genetic diversity, genetic differentiation and demographic evolution. Our results showed a real diversity of Cytochrome b compared to Beta-fibrinogen. A significant difference has been found between normal tissues and cancerous ones within Cytochrome b. these results showed an implication of mitochondrial DNA compared to nuclear DNA.


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[Ahmed Mohamed Mze, Fatimata Mbaye, Binta Keneme and Mbacke Sembene. (2017); CYTOCHROME B AND BETA-FIBRINOGEN IMPLICATION IN THE GENETIC EVOLUTION OF BREAST MALIGNANT TUMOUR IN SENEGALESE WOMEN Int. J. of Adv. Res. 5 (Jul). 503-509] (ISSN 2320-5407). www.journalijar.com


Mohamed Mze AHMED
Département de Biologie Animale, Faculté des Sciences et Techniques, Université C.A. Diop, B.P. 5005 Dakar, Sénégal.

DOI:


Article DOI: 10.21474/IJAR01/4745      
DOI URL: http://dx.doi.org/10.21474/IJAR01/4745