10Nov 2017

DNA EXTRACTION AND PCR DIAGNOSIS OF BREAST CANCER PATIENTS AMONG THE POPULATION OF TRIPURA.

  • Assistant Professor, Department of Biochemistry, Agartala Govt. Medical College, Agartala, Tripura West, India.
  • Associate Professor, Department of Biochemistry, Agartala Govt. Medical College, Agartala, Tripura West, India.
  • Junior Research Fellow, DBT Project, Department of Biochemistry, Agartala Govt. Medical College, Agartala, Tripura West, India.
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Breast cancer is a malignant tumor that starts in the cells of breast. A malignant tumor is a group of cancer cells that can grow into (invade) surrounding tissues or spread to distant areas (metastasize) of the body. Several environmental risk factors that may contribute to or hasten the development of breast cancer have been identified including mainly lifestyle, reproductive factors and family history. Mutations in the BRCA1 and BRCA2 genes profoundly increase the risk of developing breast cancer among women. BRCA1 gene is located on chromosome No. 17. The normal BRCA1 genes encode 1863 amino acids. BRCA2 gene located on chromosome No. 13 is another DNA repair gene. The normal BRCA2 genes encode 3418 amino acids. To explore the contribution of BRCA1 and BRCA2 mutations in the development of breast cancer among Indian women, we carried out DNA extraction & PCR analysis of the BRCA1 and BRCA2 genes in thirty eight (38) number of breast cancer female patients from Tripura, India.

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[Asis Debbarma1, Pradip Kumar Ghosh2, Subhojit Das1, Anubha Nandi Kar3 and Biswajit Chowdhury3. (2017); DNA EXTRACTION AND PCR DIAGNOSIS OF BREAST CANCER PATIENTS AMONG THE POPULATION OF TRIPURA. Int. J. of Adv. Res. 5 (Nov). 138-142] (ISSN 2320-5407). www.journalijar.com

Dr. Asis Debbarma
Tripura University (Central)

DOI:

Article DOI: 10.21474/IJAR01/5747      
DOI URL: http://dx.doi.org/10.21474/IJAR01/5747

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