25Aug 2019

PREDICTORS FOR SUCCESSFUL LABOUR INDUCTION WITH PGE2 IN PRIMIGRAVIDA.

  • Assistant lecture,Taif medical college,Taif university ,KSA.
  • M.B.B.S, M.C.P.S, F.C.P.S,Professor of obstetrics &gynecology,Obstetrics& gynecology department, Taif medical college, Taif university .KSA.
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Objective: To identify independent predictors of successful labor inductionWith PGE2 in Primigravidas. Methods: This retrospective study was, conducted at KAASH Hospital, TAIF, KSA. The Medical and Nursing Records of 401 Nulliparous Parturient who received PGE2 Gel for induction of labour conducted at KAASH Hospital from January 2015 to December 2015 were retrospectively reviewed. Data from medical records in the time of the study were collected for four hundred one PG?s who were admitted with documented indications for induction of labour. the administered doses of Prostin including the initial dose and the repeated doses till successful cervical dilatation and effacement and starting of labour process were recorded . The study was performed to Identify factors independently associated with successful labour induction which was defined as vaginal delivery within 24-48 hours either spontaneous or ventouse assisted vaginal delivery. Predictors of Caesarean birth and the need for only one dose of prostin were also identified. Factors included in the study were maternal age, BMI, membrane status, the dose of PGE2, gestational age, birth weight and epidural analgesia. Results.During the study period from January to December 2015. The total number of PG?s whom induced by PGE2 was 401 out of them 270 (67.3%) were NSVD 70 (17.5%) ventouse and 61 (15.2%) LSCS. Conclusion: Characteristics of the woman i.e. BMI, fetal weight and some of the individual components membrane status and gestational age, were having impact on successful/failed labor induction in form of NVD or lower segment caesarean section respectively .

  1. De Ribes C. De l?AccouchementProvoque, Dilatation du Canal Genital al?Aide de Ballonsintroduitsdans la Cavite Uterine Pendant la Grossese. Paris, Steheil, 1988.
  2. Dale HH. On some physiological actions of ergot. J Physiol 1906; 34: 163-206.
  3. Bell WB. The pituitary body. BMJ 1909;2: 1609-13.
  4. Page EW. Response of human pregnant uterus to Pitocin? tannate in oil.? Proc SocExpBiol 1943;52: 195-7.
  5. Karim SMM, Trussele RR, Patel RC, Hillier K. response of pregnant human uterus to prostaglandin F? alpha induction of labour. BMJ 1968; IV: 621-3.
  6. Macer J. Buchanan D. Yonekura ML, induction of labor with prostaglandin
  7. Gordon-Wright AP, Elder MG. Prostaglandin E2 tablets used intravaginally for the induction of labor. Br J ObstetGynecol 1984; 63:664-8.
  8. Yan X, Sun M, and Gibb W. Localization of nuclear Factor ?B (NF B) and Inhibitory Factor B (I B) in Human Fetal Membranes and Decidua at Term and Preterm Delivery. Placenta 23:288 ? 293(2002)
  9. Challis JRG, Matthews SG, Gibb W, Lye SJ. Endocrine and Paracrine Regulation of birth at Term and Preterm. 21:514-550 (2000)
  10. Gibb W. Challis JRG. Mechanisms of term and preterm labor. J ObstetGynecol Can. 24:874-883 (2002)
  11. Sanchez-Ramos L, Farah L.A, Kaunitz AM, et al. Preinduction cervical ripening with commercially available prostaglandin E2 gel: A randomized, double blind comparison with a hospital compound preparation.? Am J ObstetGynecol 1995; 173: 1079 ? 84.
  12. Stempel JE, Prins RP, Dean S. Preinduction cervical ripening: A randomized prospective comparison of the efficacy and safety of intra cervical prostaglandin E2 gel. Am J ObstetGynecol 1997; 1176:1305-9.
  13. Sanchez-Ramos, L, kaunitz, A,Glob. Libr.women?s med., (ISSN: 1756-22228) 2009; DOI 10.3843/GLOWM.101
  14. Pharmacology 2007. Rang, Ritter, Dale, Flower. Churchill Livingstone Elsevier
  15. Votta RA and Ciblis LA. Activemanagement of prolonged pregnancy. American Journal of Obstetrics and Gynecology 1993;168 (2); 557-63.
  16. Crane, JOAN M. Clinical Obstetrics and Gynecology: September 2006 ? Volume 49 ? Issue 3 ?pp 573-584.
  17. Gopalani S, Bennet K, Critchlow C. Factors predictive of failed operative vaginal delivery. Am J. obstet Gynecol. 2004 Sep;191 (3); 896-902.
  18. Clinical Guideline July 2008 Funded to produce guidelines for the NHS by NICE.
  19. WHO, 2000 and National Institute of Clinical Excellence, UK-NICE,2006
  20. Tan PC, Suguna S, Vallikannu N, Hassan J. Ultrasound and clinical predictors for Ceasarean delivery after labour induction at term. Aust N Z Obstet Gynaecol.2006
  21. Orhue AA, Unuigbe JA, Ezimokhal M. Ojo VA. Outcome of induced labour in 931 term Pregnancies. Obstet Gynaecol.1984 Jul;64(1);108-114.
  22. Greenberg MB. Cheng YW, Sillivan M. Norton ME, Hopkins LM, Caughey AB. Does length of labour vary by maternal age. Am J Obstet Gynecol.2007 Oct;197(4):e421-427.
  23. Caughey AB, Stotland NE, Washington AE, Escobar GJ. Maternal and obstetric of complications pregnancy are associated with increasing getational age term. Am J Obstet Gynecol. 2007 Feb;196(2):e151-156
  24. Nutthalapathy FS, Rouse DJ, Owen J. The association of maternal weight with caesarean risk, labour duration, and cervical dilation rate during labour induction. Obstet Gynecol.2004 Mar;103(3);452-456.
  25. Stotland NE, Hopkins LM, Caughey AB. Gestational weight gain, macrosomia, and risk of caesarean birth in nondiabetic nulliparas. Obstet Gynecol.2004 Oct;104(4):671-677.
  26. Stotland NE, eashington AE, Caughey AB. Preprenancy body mass index and the length of gestation at term. Am J Obstet Gynecol. 2007 Oct;197(4):378. E371-375.
  27. Weiss JL, Malone FD, Emig D. et al. Obesity, Obstetric complications and caesarean delivery rate- a population-based screening study. Am J Obstet Gynecol.2004.
  28. Boyd ME, Usher RH, McLean FH, Kramer MS. Obstetric consequences of postmaturity. Am J Obstet Gynecol. 1988 Feb;158(2):334-338.
  29. Gulmezoglu AM, Crowther CA, Middleton P. Induction of labour for improving birth outcomes for women at or beyond term. Cochrane Database SystRev.2006(4):CD004945.
  30. Nesbitt TS, Gilbert WM, Herrchen B. Shoulder dystocia and associated risk factors with macrosomic infants born in California . Am J Obstet Gynecol.1998 Aug;179(2):476-480.
  31. Anim-Somuah M. Smyth R. Howell C Epidural versus non-epidural or no analgesia in labour. Cochrane Database Syst Rev 2005;4:CD000331.
 

[Afnan mesfer al-otiabi and Farzana Rizwan arain. (2019); PREDICTORS FOR SUCCESSFUL LABOUR INDUCTION WITH PGE2 IN PRIMIGRAVIDA. Int. J. of Adv. Res. 7 (Aug). 1165-1172] (ISSN 2320-5407). www.journalijar.com

AFNAN MESFER AL-OTIABI
Assistant lecture Taif medical college Taif university ,KSA

DOI:

Article DOI: 10.21474/IJAR01/9607      
DOI URL: http://dx.doi.org/10.21474/IJAR01/9607

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