18Feb 2020

EVALUATION OF ANTISEPTIC PROPERTIES OF SOAPS PRODUCED WITH PHYSCIA GRISEA EXTRACT

  • Department of Crop Science, University of Nigeria, Nsukka.
  • Department of Science Laboratory Technology, University of Nigeria, Nsukka.
  • Department of Veterinary Physiology and Pharmacology, University of Nigeria, Nsukka.
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Evaluation of soaps produced with ethanol extract of Physcia grisea was carried out to determine the antiseptic properties of the ethanol extract when used in soap production. The soap production was carried out by saponification process using ethanol extract as an antiseptic agent instead of synthetic chemicals. The quality of the soap produced from antiseptic agent and the extract were assayed for antimicrobial activity using Agar Cup Diffusion Technique. The result showed that the soap had a significant activity on Escherichia coli (E. coli), which is an indicator organism for fecal contamination. The minimum inhibitory concentration (MIC) of P. grisea extract was 10 mg/ml while that of the P. grisea antiseptic soap was 12.5 mg/ml. The extract also gave a natural brownish colour to the soap. This showed that antiseptic soap produced using P. grisea extract has the advantage of possessing attractive brown colour in addition to the novel antiseptic properties.


  1. Adibe, N. and Eze, E. (2004). General Laboratory Techniques for Tertiary Institution, Mike Social Publisher, Nsukka, Enugu, Nigeria.
  2. Agboke, A. A., Eze, E. I. and Adikwu, M. U. (2005) Combined activities of colloidal silver concentration and cephalexin on Staphylococcus aureus using the agar diffusion technique; Bio-Research, 3(2): 7 ? 10.
  3. Aiello, A. E., Larson E. L. and Levy, S. B. (2007). Consumer antibacterial soaps: effective or just risky? Clin Inec Dis. 45, S137-47.
  4. Ameh, A. O, Muhammmad, J. A. and Audu, H. G. (2013). Synthesis and Characterization of antiseptic soap from neem oil and shea butter. African journal of Biotechnology, 12 (29), pp.4656-4662.
  5. Eze, E. I. (2007). Sensitivity pattern of clinical isolates of Candida albicans and Escherichia coli from HIV/AIDS patients in Nsukka area of Enugu State to Combined Physica grisea extract and standard antimicrobial agent. Nigerian Institute of Science Laboratory Technology Fellowship Thesis.
  6. Eze, E. I. and Ogonnaya, F. N. (2010). In?vitro evaluation of antimicrobial activity of ointment containing Physcia grisea extract on Candida albicans. Animal Research International, 7 (3): 1253 ? 1256.
  7. Eze, E. I. and Onumah, V. N. (2010). Evaluation of Antimicrobial Activity and Interaction of Methanolic Extract of Physcia grisea and Cephalosporin on Clinical Isolates of Streptococcus pyogenes. Bio-Research 8(2):700-702.
  8. Eze, E. I., Ezeugwu, C. N. and Adikwu, M. U. (2009). Sensitivity pattern of clinical isolates of Candida albicans from HIV/AIDS patients to combined Physcia grisea extract and tioconazole. Global Journal of Pure and Applied sciences, 15(3 & 4): 301 ? 304.
  9. Eze, E. I., Onu, E. O., Iwueze, C. A. and Ugwu, G. C. (2010). Antimicrobial activities of methanolic extract of Gongronema latifolia stem on clinical isolate of Escherichia coli from diarrhea patients. Global Journal of Pure and Applied Science, 16(4): 391 ? 394.
  10. Food and Drug Administration (FDA) United State of America (2016). Taking closer look at Antibacterial soap.
  11. Kaliyadan, F., Aboulmagd, E. and Amin, T. T. (2014). Antimicrobial activity of commercial ?antibacterial handwashes and soaps. Indian Dermatol Online J. 5 (3): 344-346.
  12. Mwambete, K. D. and Lyombe, F. (2011). Antimicrobial activity of medicated soaps commonly used by Dar es Salaam residents in Tanzania. Indian J. Pharm Sci 2011; 73:92-8.
  13. Okumura, T. and Nishikawa, Y. (1996). Gas chromatography- mass spectrometry determination of triclosans in water, sediment and fish samples via methylation with diazomethane. Anal. Chim. Acta. 325:175-184.
  14. Sooknah, R., Papavinasam, S. and Revie, R. W. (2007): In Corrosion 2007, National Association of Corrosion Engineers, Nashville, TN, 2007. Metallurgical and Material transactions A 42A, October 2011-2961.
  15. Yazdankhah, S. P. (2006). Triclosan and Antimicrobial Resistance in Bacteria: An overview. Microbial Drug Resistance 12 (2): 83-89.

[Eze Emmanuel Ikechukwu, Ogbuabor, Chinenye Odinaka, Eze Clementina Ebere and Onu Martina Chinagorom (2020); EVALUATION OF ANTISEPTIC PROPERTIES OF SOAPS PRODUCED WITH PHYSCIA GRISEA EXTRACT Int. J. of Adv. Res. 8 (2). 01-05] (ISSN 2320-5407). www.journalijar.com


Eze, Emmanuel Ikechukwu
Department of Crop Science, University of Nigeria, Nsukka

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Article DOI: 10.21474/IJAR01/10428       DOI URL: http://dx.doi.org/10.21474/IJAR01/10428


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