MIC and MBC of grapheme oxide

Graphene and graphene oxide (GO) have been extensively explored as some of the most promising biomaterials for antibacterial applications due to their unique properties: two-dimensional planar structure, large surface area, chemical and mechanical stability, superb conductivity and appropriate biocompatibility. The antibacterial applications of graphene-based materials have grown rapidly in the past few years. This property results in promising bio-applications for the design of advanced drug delivery systems by focusing on infectious and antibacterial disease of a broad range of therapeutics. In this study, we have reported the antibacterial activity of GO nano sheets (NSs) against general and more pathogenic bacteria, which is named Escherichia coli (E.coli). GO NSs with different dispersion concentrations were prepared. Then, the samples were putted intoculture plates and were inoculated with E.coli. We reported the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). The results of the GO NSs MIC and MBC tests againtsE.coli were 10 and 100 mg/ml respectively.