Study of Serum Lipid Profile AST and LDH in Pre-Elampsia and Eclampsia

Introduction: Pre-eclampsia is common medical complication of pregnancy. Pregnancy is a physiological state associated with many alterations in metabolic, biochemical, physiological, hematological and immunological processes. Material and methods: The present study was conducted on 20 normal pregnant women (Group-?), 20 pre-eclamptic pregnant women (Group-??), and 20 eclamptic pregnant women (Group-???). The blood samples were collected from all the women and analyzed for Serum Lipid profile ,AST and LDH. Results: Mean TG (255.50±32.93 vs 199.70±22.22) levels are significantly higher in group of women who had preeclampsia as compare to normal controls (p<0.001). While mean HDL-C (36.10±9.58 vs 51.50±7.98) levels were significantly lower in women with preeclampsia than in normal control subjects (p<0.001). In Case of eclampsia mean LDL cholesterol (141.3±12.62 vs 118.6 ± 12.32) are significantly higher and mean HDL-C (31.87±8.39 vs 51.5 ± 7.98) levels were significantly lower than in normal control subjects (p<0.001). Mean Serum AST& LDH concentrations were significantly higher in preeclamptic and eclamptic patients as compared to normal pregnant women.Conclusion: The assessment of serum Lipids, AST and LDH are very useful markers to identify the occurrence of the complications of pre-eclampsia and eclampsia in early pregnancy, which may reduce the risk of occurrence of disease.