ANALYSIS OF ASSISTED REPRODUCTION TECHNIQUE CYCLES IN YOUNG WOMEN WITH AFC COUNT LESS THAN FIVE IN A PUBLIC SECTOR CENTRE.

Aims and Objective(s): 1. To estimate the ART (Assisted Reproductive Techniques) outcomes in young women with AFC count less than five in a public sector ART centre in a developing country. 2. To compare the stimulation protocols used in these women Design: Retrospective data analysis. Method(s): Three year ART data analysis of 87 embryo transfer cycles in women, aged 20-35 years with AFC count less than five in a public sector ART clinic in a developing country. The data was analyzed in two groups based on the ART stimulation protocol used. We used Chi square and T tests used for statistical analysis. Results: Pregnancy rate of 44% was noted following fresh transfer cycles and 35.4% following Cryo ET cycles in women with AFC count less than five. The pregnancy rates in the agonist stimulation group and flexible antagonist groups was 46.13%and 42% respectively and comparable. Good quality embryo yield was 1.28 in antagonist group and 1.6 in agonist group (p > 0.05). Cycle cancellation due to non-recruitment was minimal in both groups. Day 5 embryo transfers, was significantly more in the long agonist group while cleavage stage embryo transfers were more in the antagonist group. Conclusions: Our stimulation protocols helped achieve satisfactory reproductive outcomes in young women with basal antral follicle count less than five. Both long agonist and antagonist stimulation protocols were comparable in their reproductive outcomes. The costs incurred in either regimen were not significantly different.