Vol. 4 (07) pp. 1817-1829 DOI: 10.21474/IJAR01/1006

Comparative Studies on CMC - Produced from Non- and Woody Lignocellulosic in Production of Biological Active Materials.

  • Cellulose and Paper Department, National Research Centre, Giza, Egypt.
  • Botany and Microbiology Department, Faculty of Science, Al-Azhar University, Cairo, Egypt.
  • CancerInstitute, Cairo University, Egypt.
  • Chemistry Department, Faculty of Science, Al-Azhar University, Cairo, Egypt.
12 Downloads 96 Views
Crossref

Abstract

The present study deals with synthesizing novel nano-cellulose derivative from non and woody lignocelluloses, and evaluating its biological activities. The biological analysis together with conventional analysis (nitrogen content, FT-IR, and TGA analysis) were detected. Optimizing the CMC and APPA conjugate preparation conditions were studied. The TEM study showed that, the synthesized viscose pulp CMC-APP derivative was 30 to 70 nm. The antimicrobial and anticancer activities of these nano- CMC derivatives against four bacterial strains andsix fungal strains, as well as MCF-7 were tested. Among all the tested microorganisms and MCF-7 the synthesized nano-cellulose conjugate possible used as safety medicine for microbial infections and cancers, with MIC for Gram-positive bacteria 2.0?g/mL in viscose pulp conjugate, and gram-negative 4.0?g/mL in bagasse pulp. The bagasse pulp conjugate appearing has high antifungal activity Aspergillus awamori4.0?g/ml. Viscose pulp conjugate shows the anticancer activity with IC50 for MCF-7 breast cancers 32 µg/ml.

Keywords

Article Analytics

How to Cite This Article

Houssni El-Saied, Altaf H. Basta, Hussein El-Sheikh, Essam H. Abdel-Shakour, Ahmed A.El-Henawy, Mervat M. El-Deftar and Mohamed S. Hasanin. (2016); Comparative Studies on CMC - Produced from Non- and Woody Lignocellulosic in Production of Biological Active Materials., Int. J. of Adv. Res., 4 (07), 1817-1829, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/1006

Corresponding Author

Mohamed Sayed Hasanin