BIOLOGICAL SYNTHESIS AND CHARACTERIZATION OF COPPER OXIDE NANOPARTICLES USING ANTIGONON LEPTOPUS LEAF EXTRACT AND THEIR ANTIBACTERIAL ACTIVITY

During the last two decades, the biosynthesis of nanoparticles has received considerable attention due to the growing need to develop environmentally sociable technologies in nanoparticle synthesis. The routinely used chemical and physical methods in the synthesis of nanoparticles employ toxic chemicals and non-polar solvents. Therefore, there is a need for the development of eco-friendly process to synthesize nanoparticles through green chemistry using plants and microorganisms. The present study has been taken to synthesize copper oxide nanoparticles (CuO-NP’s) using green biosynthetic method by reduction of copper sulphate solution with Antigonon leptopus leaf extract which acts as reducing agent and efficient stabilizer at room temperature. Synthesized nanoparticles were characterized using UV-visible spectrophotometer, FT-IR, X-ray diffraction and SEM methods. The morphology of the nanoparticles are crystalline, more or less spherical, cuboid and planar nanoclusters with panoramic view and range from 110-280nm in size. XRD analysis has given a clear picture on the presence crystalline cubic phase of monoclinic Copper oxide nanoparticles. Copper oxide nanoparticles exhibited potent antibacterial activity against gram positive and moderate activity against gram negative bacterial strains tested. The present study successfully demonstrates the convenient utilization of Antigonon leptopus leaf extract to get structurally and morphologically interesting and potential antibacterial Copper oxide nanoparticles.