A NOVEL APPROACH FOR BIOTECH: ORGAN-ON-CHIP
- B.Tech (Electronics and Telecommunication), SVKMs NMIMS, Shirpur, Maharashtra, India.
- Member, IEEE, Mukesh Patel Technolgy Park, Babulde, Bank of Tapi River NH 3, Shirpur, Maharashtra 425405.
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Remarkable efforts have been dedicated on the studies of cultured cells over the last few years, which have given us a new insight into the biological control and provided us considerable knowledge about the human pathophysiology. With the immerging technology of microfluidic Lab-on-a-chip we have been able to analyse intercellular communications and tissue-tissue interactions in a more convenient and comprehensive manner. The microfluidic Lab-on-a-chip is undoubtedly the most optimistic platform to address the inherent complicacy of cellular system with 4D analysis and huge experimental parallelization on a single cell level. In this paper, we have summarized a few recent examples of studies that provide a glimpse of what is now possible using human organs-on-chips, and the unique advantages this approach can provide beyond those offered by existing culture systems used to study intercellular communication in vitro.
[Nilesh Padhi and Shashikant Patil. (2016); A NOVEL APPROACH FOR BIOTECH: ORGAN-ON-CHIP Int. J. of Adv. Res. 4 (Sep). 1826-1834] (ISSN 2320-5407). www.journalijar.com