MORPHOLOGY AND SERUM IGE LEVELS IN RECURRENT ACUTE APPENDICITIS.

The pathophysiology and morphology of recurrent appendicitis has not been well studied. This study was conducted to examine the subtle morphological changes in recurrent appendicitis and to compare the serum IgE levels with appropriate controls. The clinical, laboratory and morphological findings of the appendicitis were compared between the three groups namely, acute, recurrent and control. No significant differences were found in the clinical, laboratory, and morphological parameters between acute appendicitis presenting for the first time and recurrent appendicitis. Repeated attacks in recurrent appendicitis may indicate a predisposition to type I hypersensitivity. The appendix in recurrent appendicitis does not undergo chronic or reparative changes to any significant extent.