ALCOHOL INDUCED OXIDATIVE STRESS IN TESTES OF EXPERIMENTAL ANIMALS
- Asst. Professor, Department of Biochemistry, Mahe Institute of Dental Sciences and Hospital, Mahe.
- School of Health Sciences, University of Calicut.
- Asst. Professor, Department of Microbiology, Mahe Institute of Dental Sciences and Hospital, Mahe.
Abstract
A study was conducted to evaluate the alcohol induced oxidative Stress (OS) in the testes of experimental animals. Albino rats of Wister stain weighing 200-220 g were used for the study. The experimental groups received 1.6 g of ethanol/kg of body weight/day for 12 weeks. It was observed that alcohol used for a long period caused significant OS in the testes as a result of the generation of Super Oxide (SO) radical due to the alcohol metabolism. A significant reduction in glutathione and increased in barbituric acid reactive substances were observed. SO dismutase activity and glutathione reductase activity decreased significantly in the experimental group.
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Gireesh Kumar K.M, Sumesh V.K and Rajeswari V. (2022); ALCOHOL INDUCED OXIDATIVE STRESS IN TESTES OF EXPERIMENTAL ANIMALS, Int. J. of Adv. Res., 10 (01), 01-05, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/14002
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