A CROSS SECTIONAL STUDY OF NUTRITIONAL ASSESSMENT IN CHRONIC KIDNEY DISEASE PATIENTS.
- Mahatma gandhi medical college and research institute pondicherry ? 607402, india.
- Abstract
- References
- Cite This Article as
- Corresponding Author
Background: Chronic kidney disease is one of the global burdens, more so in developing countries where the medical facility is not abundantly available in the rural areas. Along with comorbid conditions, protein energy malnutrition plays a vital role in progression of renal disease. Proper diet management can decrease the rapid progression of chronic kidney disease. Though many studies have been done in other countries regarding the nutritional assessment in chronic kidney disease patients, it is mandatory to assess the prevalence of malnutrition in the rural or urban population of developing country. Methods: 100 consecutive patients were enrolled for the study. After obtaining written consent, history regarding the demographic data, duration of the disease, associated clinical features and 24 hour dietary recall were obtained. Then basic anthropometric parameters such as height, weight, Body Mass Index, skin fold thickness and mid arm circumference was measured. Later laboratory parameters such as haemoglobin, serum urea, serum creatinine, calcium, phosphorus, uric acid, total protein and serum albumin was measure. Results: The prevalence of protein energy malnutrition is 36% in our study which is more prevalent in the male gender as the total number of male patients are predominant in our study. And the patients in the initial stages of CKD are not aware of low protein diet. It is advisable to introduce dietary management along with medical management in all stages of chronic kidney disease patients. Conclusion: The incidence of PEM among the study population is nearly high but proper nutritional knowledge is lacking in these patients. Hence it is mandatory to introduce dietary management along with medical management in all stages of CKD so that rapid progression to end stage renal disease can be delayed.. It is also identified that severe protein energy malnutrition itself increases the mortlity of the patients. Small population, unequal gender and age distribution, shorter time period and unavailability of data for stage 1 CKD were the major limitations of the study. Hence in the future rectifying all the above said limitations such a study has to repeated periodically for better understanding of the study which will further improve the patient care and may help in reducing the early progression of the kidney disease.a large randomised control study can throw mucy light in the management of PEM in CKD patients.
- Jones CA, McQuillan GM, Kusek JW, Eberhardt MS, Herman WH, Coresh J, Salive M, Jones CP, Agodoa NKF KDOQI Guidelines. Third Natl Health Nutr Exam Surv. Am J Kidney Dis:32:992-999.
- Fouque J. Kopple KK-Z. A proposed nomenclature and diagnostic criteria for protein?energy wasting in acute and chronic kidney disease. Am J Kidney Dis. 36 (2000):362?367.
- Chung M, Chan JA, Moorthy D, Hadar N, Ratichek SJ, Concannon TW, et Biomarkers for Assessing and Managing Iron Deficiency Anemia in Late-Stage Chronic Kidney Disease: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 83. 2013 [cited 2016 Sep 3]; Available from: http://www.ncbi.nlm.nih.gov/books/NBK143610/
- Burrowes JD, Cockram DB, Dwyer JT, Larive B, Paranandi L, Bergen C, et Cross-sectional relationship between dietary protein and energy intake, nutritional status, functional status, and comorbidity in older versus younger hemodialysis patients. J Ren Nutr Off J Counc Ren Nutr Natl Kidney Found. 2002 Apr;12(2):87?95.
- Kalantar-Zadeh K, Tortorici AR, Chen JLT, Kamgar M, Lau W-L, Moradi H, et Dietary restrictions in dialysis patients: is there anything left to eat? Semin Dial. 2015 Apr;28(2):159?68.
- Velludo CMO, Kamimura MA, Sanches FMR, Lemos MM, Canziani MEF, Pupim LB, et Prospective evaluation of waist circumference and visceral adipose tissue ?in ?patients ?with ?chronic ?kidney ?disease. ?Am ?J ?Nephrol. 2010;31(2):104?9.
- Teo BW, Toh QC, Chan XW, Xu H, Li JL, Lee Assessment of muscle mass and its association with protein intake in a multi-ethnic Asian population: relevance in chronic kidney disease. Asia Pac J Clin Nutr. 2014;23(4):619?25.
- Segall L, Moscalu M, Hogaş S, Mititiuc I, Nistor I, Veisa G, et Protein- energy wasting, as well as overweight and obesity, is a long-term risk factor for mortality in chronic hemodialysis patients. Int Urol Nephrol. 2014 Mar;46(3):615?21.
- de Oliveira CMC, Kubrusly M, Mota RS, Choukroun G, Neto JB, da Silva CAB. Adductor pollicis muscle thickness: a promising anthropometric parameter for patients with chronic renal J Ren Nutr Off J Counc Ren Nutr Natl Kidney Found. 2012 May;22(3):307?16.
- Tsimihodimos V, Mitrogianni Z, Elisaf Dyslipidemia Associated with Chronic Kidney Disease. Open Cardiovasc Med J. 2011 Feb 24;5:41?8.
- Khatiwada S, Rajendra KC, Gautam S, Lamsal M, Baral Thyroid dysfunction and dyslipidemia in chronic kidney disease patients. BMC Endocr Disord. 2015;15:65.
- Yanowsky-Escatell FG, Pazar?n-Villase?or L, Andrade-Sierra J, Zambrano- Velarde MA, Preciado-Figueroa FM, Santana-Arciniega CJ, et [Association of serum albumin and subjective global assessment on incident peritoneal dialysis patients]. Nutr Hosp. 2015;32(6):2887?92.
- Khan DA, Ahmad TM, Qureshil AH, Halim A, Ahmad M, Afzal Assessment of proteinuria by using protein: creatinine index in random urine sample. JPMA J Pak Med Assoc. 2005 Oct;55(10):428?31.
- Noce A, Vidiri MF, Marrone G, Moriconi E, Bocedi A, Capria A, et Is low- protein diet a possible risk factor of malnutrition in chronic kidney disease patients? Cell Death Discov. 2016;2:16026.
- Jiang Z, Zhang X, Yang L, Li Z, Qin Effect of restricted protein diet supplemented with keto analogues in chronic kidney disease: a systematic review and meta-analysis. Int Urol Nephrol. 2016 Mar;48(3):409?18.
- Zhang M, Zhao Y, Zhu [Effect of Individualized Low-protein Diet Intervention on Renal Function of Patients with Chronic Kidney Disease]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2015 Aug;37(4):384?91.
- Liu Z, Su G, Guo X, Wu Y, Liu X, Zou C, et Dietary interventions for mineral and bone disorder in people with chronic kidney disease. Cochrane Database Syst Rev. 2015;(9):CD010350.
- Obi Y, Qader H, Kovesdy CP, Kalantar-Zadeh Latest Consensus and Update on Protein Energy-Wasting in Chronic Kidney Disease. Curr Opin Clin Nutr Metab Care. 2015 May;18(3):254?62.
- Ohsawa M, Tamura K, Wakui H, Kanaoka T, Azushima K, Uneda K, et Effects of pitavastatin add-on therapy on chronic kidney disease with albuminuria and dyslipidemia. Lipids Health Dis [Internet]. 2015 Dec 9 [cited 2016 Sep 4];14. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673714/
- Ahmadi S-F, Zahmatkesh G, Ahmadi E, Streja E, Rhee CM, Gillen DL, et Association of Body Mass Index with Clinical Outcomes in Non-Dialysis- Dependent Chronic Kidney Disease: A Systematic Review and Meta-Analysis. Cardiorenal Med. 2015 Dec;6(1):37?49.
- Sakao Y, Ojima T, Yasuda H, Hashimoto S, Hasegawa T, Iseki K, et Serum Creatinine Modifies Associations between Body Mass Index and Mortality and Morbidity in Prevalent Hemodialysis Patients. PloS One. 2016;11(3):e0150003.
- Costanzo P, Cleland JGF, Pellicori P, Clark AL, Hepburn D, Kilpatrick ES, et al. The obesity paradox in type 2 diabetes mellitus: relationship of body mass index to prognosis: a cohort Ann Intern Med. 2015 May 5;162(9):610?8.
- Calabia J, Arcos E, Carrero JJ, Comas J, Vall?s Does the obesity survival paradox of dialysis patients differ with age? Blood Purif. 2015;39(1?3):193?9.
- Mohebi R, Simforoosh A, Tohidi M, Azizi F, Hadaegh Obesity Paradox and Risk of Mortality Events in Chronic Kidney Disease Patients: A Decade of Follow-up in Tehran Lipid and Glucose Study. J Ren Nutr Off J Counc Ren Nutr Natl Kidney Found. 2015 Jul;25(4):345?50.
- Park J, Ahmadi S-F, Streja E, Molnar MZ, Flegal KM, Gillen D, et Obesity Paradox in End-Stage Kidney Disease Patients. Prog Cardiovasc Dis. 2014;56(4):415?25.
- Vashistha T, Mehrotra R, Park J, Streja E, Dukkipati R, Nissenson AR, et Effect of age and dialysis vintage on obesity paradox in long-term hemodialysis patients. Am J Kidney Dis Off J Natl Kidney Found. 2014 Apr;63(4):612?22.
- Davis E, Campbell K, Gobe G, Hawley C, Isbel N, Johnson Association of anthropometric measures with kidney disease progression and mortality: a retrospective cohort study of pre-dialysis chronic kidney disease patients referred to a specialist renal service. BMC Nephrol. 2016;17(1):74.
- Rao P, Reddy GC, Kanagasabapathy Malnutrition-inflammation- atherosclerosis syndrome in Chronic Kidney disease. Indian J Clin Biochem. 2008 Jul;23(3):209?17.
- Jadeja YP, Kher Protein energy wasting in chronic kidney disease: An update with focus on nutritional interventions to improve outcomes. Indian J Endocrinol Metab. 2012 Mar;16(2):246?51.
- Mohanty BP, Ganguly S, Mahanty A, Sankar TV, Anandan R, Chakraborty K, et DHA and EPA Content and Fatty Acid Profile of 39 Food Fishes from India. BioMed Res Int. 2016;2016:4027437.
- Kwon YE, Kee YK, Yoon C-Y, Han IM, Han SG, Park KS, et Change of Nutritional Status Assessed Using Subjective Global Assessment Is Associated With All-Cause Mortality in Incident Dialysis Patients. Medicine (Baltimore). 2016 Feb;95(7):e2714.
- Sedhain A, Hada R, Agrawal RK, Bhattarai GR, Baral Assessment of Nutritional Status ?of ?Nepalese ?Hemodialysis ?Patients ?by ?Anthropometric Examinations and Modified Quantitative Subjective Global Assessment. Nutr Metab Insights. 2015;8:21?7.
- Kutsal DA, K?rşat S, İnci A, Ulman C, Ozan?t?k The relationship between malnutrition subgroups and volume parameters in pre-dialysis patients. Saudi J Kidney Dis Transplant Off Publ Saudi Cent Organ Transplant Saudi Arab. 2016 Jan;27(1):81?7.
- Hoppe K, Schwermer K, Klysz P, Radziszewska D, Sawatiuk P, Baum E, et Cardiac Troponin T and Hydration Status as Prognostic Markers in Hemodialysis Patients. Blood Purif. 2015;40(2):139?45.
- Guerra DC, Rodrigues Neto Ang?loco L, Furtado WR, Barbosa Coelho E, Garcia Chiarello Late referral for chronic kidney disease patients: nutritional point of view. Nutr Hosp. 2015;31(3):1286?93.
- Yaghoubi F, Ahmadi F, Lesanpezeshki M, Mahdavi Mazde A study on the association of serum fibroblast growth factor-23 with various indices of chronic kidney disease patients not yet on dialysis. J Ren Inj Prev. 2016;5(2):104?7.
- Cordeiro AC, Qureshi AR, Lindholm B, Amparo FC, Tito-Paladino-Filho A, Perini M, et Visceral fat and coronary artery calcification in patients with chronic kidney disease. Nephrol Dial Transplant Off Publ Eur Dial Transpl Assoc - Eur Ren Assoc. 2013 Nov;28 Suppl 4:iv152-159.
- Cafka M, Rroji M, Seferi S, Barbullushi M, Burazeri G, Spahia N, et Inflammation, Left Ventricular Hypertrophy, and Mortality in End-stage Renal Disease. Iran J Kidney Dis. 2016 Jul;10(4):217?23.
- Miranda-D?az AG, Pazar?n-Villase?or L, Yanowsky-Escatell FG, Andrade- Sierra Oxidative Stress in Diabetic Nephropathy with Early Chronic Kidney Disease. J Diabetes Res [Internet]. 2016 [cited 2016 Sep 4];2016. Available from: ?http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971321/
- Loutradis C, Skodra A, Georgianos P, Tolika P, Alexandrou D, Avdelidou A, et Diabetes mellitus increases the prevalence of anemia in patients with chronic kidney disease: A nested case-control study. World J Nephrol. 2016 Jul 6;5(4):358?66.
- Stenvinkel P, Heimb?rger O, Paultre F, Diczfalusy U, Wang T, Berglund L, et Strong association between malnutrition, inflammation, and atherosclerosis in chronic renal failure. Kidney Int. 1999 May;55(5):1899?911.
- Palmer SC, Gardner S, Tonelli M, Mavridis D, Johnson DW, Craig JC, et Phosphate-Binding Agents in Adults With CKD: A Network Meta-analysis of Randomized Trials. Am J Kidney Dis Off J Natl Kidney Found. 2016 Jul 22;
- Shaheen FAM, Kurpad R, Al-Sayyari AA, Souqiyyeh MZ, Aljubori H, El Baz T, et Multinational observational study on clinical practices and therapeutic management of mineral and bone disorders in patients with chronic kidney disease stages 4, 5, and 5D: The OCEANOS study. Saudi J Kidney Dis Transplant Off Publ Saudi Cent Organ Transplant Saudi Arab. 2016 Mar;27(2):290?304.
- Effect of Vitamin B 12 supplementation on serum homocysteine in patients undergoing hemodialysis: A randomized controlled trial Tayebi A, Biniaz V, Savari S, Ebadi A, Shermeh MS, Einollahi B, Rahimi A - Saudi J Kidney
[Dr. S. Nirmala. (2018); A CROSS SECTIONAL STUDY OF NUTRITIONAL ASSESSMENT IN CHRONIC KIDNEY DISEASE PATIENTS. Int. J. of Adv. Res. 6 (Apr). 1184-1202] (ISSN 2320-5407). www.journalijar.com
MD General Medicine Post Graduate