INTRADURAL EXTRAMEDULLARY SPINAL CORD TUMORS: A RETROSPECTIVE STUDY OF LOCATIONS, TUMOR TYPES, AND SURGICAL OUTCOME
- Mch (neurosurgery).
- surgery post graduate
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Introduction: Intradural extramedullary spinal cord tumors (IESCT) account for approximately two thirds of all intraspinal neoplasms. The purpose of this study was to determine short- and long-term outcomes of surgery in patients with IESCT, and to study the clinical features that could be helpful in treatment of patients with these lesions. Methods: A retrospective review of 25 operative IESCT cases between 2012 and 2014 was performed. Outcomes were scored at one month and at mean follow-up of 9 months postoperatively. In addition, patient demographics, tumor subtypes and locations were also considered. Statistical analysis was calculated utilizing Chi-square and Student's t-tests. Results: There were 8 men and 17 women (mean age 48 y/o, range 18-87 y/o). Men presented at a younger age than women (44 vs 53 y/o, P<0.02). 18 (72%) patients presented with severe radiculopathy and/or myelopathy. The remaining 7 (28%) had symptoms typical of disc herniation. Mean duration of symptoms prior to diagnosis was 11 months. Schwannomas (10 patients) had the longest mean duration of symptoms (14.9 months), followed by meningiomas (8 patients, 8.4 months), and ependymomas (7 patients, 2 months). Conclusions: Intradural extramedullary tumors, easily detected by MRI, are mostly benign and excellent clinicoradiological results can be obtained by microneurosurgery. Therefore, more active surgical approaches by neurosurgeons are recommended to decrease morbidity.
- Porchet F, Sajadi A, Villemure JG. Spinal tumors: clinical aspects, classification and surgical treatment. Schweiz Rundsch Med Prax. 2003;92:1897-1905.
- Hufana V, Tan JSH, Tan KK. Microsurgical treatment for spinal tumors. Singapore med J. 2005;46:74-77.
- Albanese V, Platania N. Spinal intradural extramedullary tumors. Personal experience. J Neurosurg Sci.
- 2002;46:18-24.
- Slin'ko EI, Al-Qashqish II. Intradural ventral and ventrolateral tumors of the spinal cord: surgical treatment and results. Neurosurg Focus. 2004;15:ECP2.
- Peker S, Cerci A, Ozgen S, Isik N, Kalelioglu M, Pamir MN. Spinal meningiomas: evaluation of 41 patients. J Neurosurg Sci. 2005;49:7-11.
- Prevedello DM, Koerbel A, Tatsui CE, Truite L, Grande CV, Ditzel LF, Araujo JC. Prognostic factors in the treatment of the intradural extramedullary tumors: a study of cases. Arq Neuropsiquiatr. 2003;61:241-247.
- Odom GL, Finney W, Woodhall B. Cervical disk lesions. JAMA. 1958;166:23-28.
- Yasargil MG, DeLong WB, Guarnaschelli JJ: Complete microsurgical excision of cervical extramedullary and intramedullary vascular malformations. Surg Neurol. 1975;4:211-24.
- Schaller B. Spinal meningioma: relationship between histological subtypes and surgical outcome? 2005;75:157-161.
- Gelabert-Gonzalez M. Primary spinal cord tumors. An analysis of a series of 168 patients. Rev Neurol. 2007;44:269-274.
- Sandalcioglu IE, Gasser T, Asgari S, Lazorisak A, Engelhorn T, Egelhof T, Stolke D, Wiedemayer H. Functional outcome after surgical treatment of intramedullary spinal cord tumors: experience with 78 patients. Spinal Cord. 2005;43:34-41.
- Allen JC, Aviner S, Yates AJ, Boyett JM, Cherlow JM, Turski PA, et al. Treatment of high-grade spinal cord astrocytoma of children with "8 in 1" chemotherapy and radiotherapy: a pilot study of CCG-945. Children's Cancer Group. J Neurosurg. 1998;88:215-220.
- Cohen AR, Wisoff JH, Allen JC, Epstein F. Malignant astrocytomas of the spinal cord. J Neurosurg. 1989;70:50-54.
- el-Mahdy W, Kane PJ, Powell MP, Crockard HA: Spinal intradural tumors: Part I - Extramedullary. Br J Neurosurg. 1999;13:550-557.
- Garrido P, Laher-Mooncey S, Murphree NL, Jonker N, Levy LF, and Makarawo S. Neoplasms involving the spinal cord in Zimbabweans: an analysis of 262 cases. Cent Afr J Med. 1994;40:201-204.
- Fromme K, Miltner FO, Klawki P, Friedrich M. Spinal cord monitoring during intraspinal extramedullary tumor operations (peroneal nerve evoked responses). Neurosurg Rev. 1990;13:195-9.
- Gelabert-Gonzalez M, Garcia-Allut A, Martinez-Rumbo R. Spinal meningiomas. Neurocirurgia (Astur). 2006;17:125-131.
- Cohen-Gadol AA, Zikel OM, Koch CA, Scheithauer BW, Krauss WE. Spinal meningiomas in patients younger than 50 years of age: a 21-year experience. J Neurosurg. 2003;98:258-63.
- Queckel LG, Versteege CW. The "dural tail sign" in MRI of spinal meningiomas. J Comput Assist Tomogr. 1995;19:890-2.
- Souweidane MM, Benjamin V. Spinal cord meningiomas. Neurosurg Clin North Am. 1994;5:283-291.
- Wippold FJ 2nd, Smirniotopoulos JG, Moran CJ, Suojanen JN, Vollmer DG. MR imaging of myxopapillary ependymoma: findings and value to determine extent of tumor and its relation to intraspinal structures. AJR Am J Roentgenol. 1995;165:1263-7.
- Brazier JE, Harper R, Jones NM, O'Cathain A, Thomas KJ, Usherwood T, Westlake L. Validating the SF-36 health survey questionnaire: new outcome measure for primary care. BMJ 1992;305:160-4.
- Nurick S. The pathogenesis of the spinal cord disorder associated with cervical spondylosis. Brain 1972; 95:87-100.
Sandeep Inchnalkar, Kashif Ansari, Suraj Mahadik and Nikunj Shekhada. (2017); INTRADURAL EXTRAMEDULLARY SPINAL CORD TUMORS: A RETROSPECTIVE STUDY OF LOCATIONS, TUMOR TYPES, AND SURGICAL OUTCOME, Int. J. of Adv. Res., 5 (01), 2186-2190, ISSN 2320-5407. DOI URL: https://dx.doi.org/10.21474/IJAR01/2995






