28Feb 2017

THE MOST COMMON GENETIC DISEASE IN HAIL AND DISEASES RELATED TO CONSANGUINITY.

  • From the medicine and general surgery collage, University ofHail, Hail, Saudi Arabia.
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Background and objective: There are common genetic diseases in Hail,but the information about it are still limited.The objective of this cross-sectional study was to detect the most common genetic disease and the risk factor of consanguinity on genetic diseases in Hail. Subjects and methods: The study samples were determined by multistage probability random sampling procedure. Genetic diseases were obtained from 500 papers and electronic questionnaires. The data were analyzed by using SPSS and calculator. Results:The proportions of genetic diseases were ordered from highest to lowest as follow: Type 1 Diabetes Mellitus(20%), Congenital Heart Disease(9%), breast cancer(8.2%), Down syndrome (6.4%),Sickle cell disease(3.8%), Muscular Dystrophy (1.8%) and Thalassemia (1%).However, 49.6% of sample answered the question were consanguineous. The proportions showed Thalassemia was the highest disease affected by consanguinity relationship with (100%, p= 0.023),followed Sickle cell disease (73.68%,p= 0.032) andbreast cancer (34.14%,p= 0.039). Conclusion: The data suggested that the most common genetic disease in Hail is Type1 Diabetes Mellitus and consanguinity is one of the risk factor on some of these genetic diseases as Thalassemia, Sickle cell disease and breast cancer.

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[Halah M. Alrshedy, Eman M. Alshammary, Sarah M. Saud and Kholoud M. Alzmi. (2017); THE MOST COMMON GENETIC DISEASE IN HAIL AND DISEASES RELATED TO CONSANGUINITY. Int. J. of Adv. Res. 5 (Feb). 2555-2559] (ISSN 2320-5407). www.journalijar.com

Kholoud M. Alzmi
medicine and general surgery collage, University ofHail, Hail, Saudi Arabia.

DOI:

Article DOI: 10.21474/IJAR01/3440      
DOI URL: https://dx.doi.org/10.21474/IJAR01/3440

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