28Feb 2017

HEMORRHAGIC GLIOBLASTOMA MULTIFORM: PREVALENCE, PREDISPOSING FACTORS AND PROGNOSIS AMONG ADULT KFMC PATIENTS.

  • Neurosurgery consultant, Affiliation: Director neuroscience department King Fahad Medical City, Ministry of Health, Riyadh, Saudi Arabia.
  • Radiation oncology consultant, chairman of radiation oncology department at King Fahad Medical City, Ministry of Health, Riyadh, Saudi Arabia.
  • Medical intern, Affiliation: King Saud bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs (MNG-HA) Jeddah, Saudi Arabia.
  • Student at College of Medicine, student number: 320302013, King Saud bin Abdulaziz University for Health Sciences, Jeddah Saudi Arabia.
  • Student at College of Medicine, student number: 320701018, Affiliation :King Saud bin Abdulaziz University for Health Sciences, Jeddah Saudi Arabia.
  • Department of statistics, university of leeds, leeds LS2 9JT, United Kingdom; Department of mathematics, college of science and humanitarian studies, Prince Sultan Bin Abdulaziz University, Saudi Arabia.
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Context: glioblastoma multiform (GBM) is the stage four of glioblastoma tumor(1). It is the most common primary intra-cranial tumors(2). GBM can be presented by intracranial hemorrhage (ICH) with an incidence between 1 – 10 % and usually occur in the late course of the disease. The general prognosis of GBM with ICH is poor and worsen in elderly(8)(5). Aims: Determining the effect of the hemorrhage on the disease prognosis, exploring the prevalence and predisposing factors. Methods: A retrospective medical record review had performed for patients diagnosed with GBM between 2008 through 2013 at national neuroscience institute in King Fahad Medical City. Inclusion criteria are male and female with age more than 18 years old diagnosed with glioblastoma multiform grade four and were followed in the King Fahad Medical City Clinic. The exclusion criteria is any patients with the hemolytic disorder. Results: . A total of 87 out of 530 patients with GBM were identified. 15 (17.2%) of GBM patients have ICH while 72(82.8%) non-hemorrhagic. 61 (70.1%) were male while 26 (29.9%) were female. No difference between prognosis between hemorrhagic and non-hemorrhagic GBM patients. Tumor size, and gender are not predisposing factors. Conclusion: there were no difference in the prognosis and between hemorrhagic glioblastoma multiform and non-hemorrhagic and gender and Tumor size are not predisposing factors.

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[Ahmed Lary, Ali Balbaid, Abdullah Hamed Alnemari, Abdullah Abdulatif Allehiany, Omar Naji Alnabihi and Khaled Mubarek Alqahtani. (2017); HEMORRHAGIC GLIOBLASTOMA MULTIFORM: PREVALENCE, PREDISPOSING FACTORS AND PROGNOSIS AMONG ADULT KFMC PATIENTS. Int. J. of Adv. Res. 5 (Feb). 2580-2583] (ISSN 2320-5407). www.journalijar.com

Dr.Khaled Mubarek Alqahtani
department of statistics, university of leeds, leeds LS2 9JT, United Kingdom; Department of mathematics, college of science and humanitarian studies, Prince Sultan Bin Abdulaziz University

DOI:

Article DOI: 10.21474/IJAR01/3444      
DOI URL: https://dx.doi.org/10.21474/IJAR01/3444

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