COMPARATIVE STUDY OF INTRAOPERATIVE COMPLICATIONS IN PSEUDOEXFOLIATION SYNDROME WITH NORMAL PATIENTS IN CATARACT SURGERY.

Background And Objective: Pseudoexfoliation syndrome is an age–related systemic diseasemanifesting itself primarily in the eyes which is characterized by the accumulation of microscopic granular amyloid-like protein fibres. Studies have shown that these patients have higher rates of intraoperative complications compared to the patients without the condition. This study was undertaken to determine and compare the intraoperative complications in Pseudoexfoliation patients with Normal patients in cataract surgery. Methods: It’s a hospital based Prospective observational study of 100 patients, 50 patients having Pseudoexfoliation syndrome and 50 patients without Pseudoexfoliation syndrome attending department of Ophthalmology, D. Y. Patil hospital and Research Institute, Kolhapur, between May 2014-April 2016. Results:The average age of patients was 66 years, with male predominance and with a higher incidence of bilateral involvement.13 (26%) patients with Pseudoexfoliation syndrome had intraoperative complications while 4(8%) patients without Pseudoexfoliation syndrome had intraoperative complication. Among all complications, the incidence among patients with Pseudoexfoliation syndrome and patients without Pseudoexfoliation syndrome were 6(12 %) and 2(4%) for Zonular dehiscence, 4(8%) and 1(2%) patient for Posterior Capsular Rent and 3(6%) and 1(2%) patient for Vitreous loss respectively. Conclusion: Inadequate mydriasis is one of the major preoperative complication with Pseudoexfoliation syndrome which has a bearing on the intraoperative complications. With proper preparation, Small Incision Cataract Surgery can be performed in this group of patients. In conclusion, with appropriate preoperative, intraoperative and postoperative care the risks of complications can be minimized and favorable outcomes can be achieved in cataract surgery with Pseudoexfoliation syndrome.