Vol. 5 (02) pp. 2269-2276 DOI: 10.21474/IJAR01/3404

INFLUENCES OF NIGELLA SATIVA ON ANTIOXIDANT ACTIVITY IN BROILERS TOXIFIED WITH SYNTHETIZED ORGANOPHOSPHORUS COMPOUNDS.

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  • Department of Chemistry, Faculty of Science, Suez Canal University, Ismailia, Egypt, 41522.
  • Department of Animal Hygiene, Zoonosis & Animal Behavior, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt, 41522.
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Abstract

Nigella has historical and religious uses for preventing and treating many different kinds of diseases. Influences of Nigella on bird performance, biochemical, antioxidant and immunological status in birds toxified with synthetized diazinon were studied. 150 broiler chick were received and divided into three groups; G1 and G2 were supplemented with Nigella (1.4 gm / 100 gm; 2.8 gm / 100 gm ration; respectively) and G3 is control. G1 and G2were toxified with synthetized diazinon (100 ppm / 1 L drinking water). A total of 180 samples (60 serum, 60 plasma and 60 intestinal swab) were collected during the study period. The results revealed the ability of Nigella to maintain biochemical parameters as TP; Alb; Glob; ALT; AST; Urea and Creatinine after prolonged deviation. Glutathione peroxidase was sharply decreased, Glutathione Reductase was sharply increased indicating the stimulation action. Superoxide Dimutase was significantly increased until the 4th week of age followed by significant decrease. Immunoglobines (IgG, IgM) were increased at the 2nd week of age followed by significant decrease by the protective effects of Nigella. On the other hand, IgE was increased and maintained at high levels. A sharp decline in both Total Bacterial Count and Total Enterobacteriaceae Count until the 4th week of age followed by sharp increase in both types in all treated groups suggesting the failure of the protective action. A follow up with the supplementation in higher doses may protect from the further changes in biochemical, antioxidant, immunological and bacteriological aspects.

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How to Cite This Article

Al Shimaa M Ibrahim, El-Said E Esmail and Essam S Soliman. (2017); INFLUENCES OF NIGELLA SATIVA ON ANTIOXIDANT ACTIVITY IN BROILERS TOXIFIED WITH SYNTHETIZED ORGANOPHOSPHORUS COMPOUNDS., Int. J. of Adv. Res., 5 (02), 2269-2276, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/3404

Corresponding Author

Essam Samir Soliman
Department of Animal Hygiene, Zoonoses and Animal Behavior, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt
Creative Commons Attribution 4.0 This work is licensed under a Creative Commons Attribution 4.0 International License.